2019 年第 39 卷第 11 期 - 临床与病理杂志

论著 Original Article

FGFR1抑制剂PD173074经诱导自噬逆转人肺腺癌HCC827细胞对厄罗替尼耐药
FGFR1 inhibitor PD173074 reverses HCC827 cells resistance to erlotinib via activating autophagy

刘勇世, 张志培, 赖远阳, 李小飞, 王小平, 雷杰
LIU Yongshi, ZHANG Zhipei, LAI Yuanyang, LI Xiaofei, WANG Xiaoping, LEI Jie

摘要 Abstract PDF Pages: 2341-2348

慢病毒介导的shRNA靶向干扰NSD2三阴乳腺癌稳定细胞株的建立
Establishment of a Triple-negative Breast Cancer Cell Line with Stable Knockdown of NSD2 Gene via Lentivirus-mediated Interference

刘秀敏, 潘云, 宁春萌, 高波
LIU Xiumin, PAN Yun, Ning Chunmeng, GAO Bo

摘要 Abstract PDF Pages: 2349-2355

维生素E对CBA小鼠年龄相关性听力损失的保护作用及其机制
Protective effect and mechanism of vitamin E on age related hearing loss in CBA mice

李兴程, 周涛
LI Xingcheng, ZHOU Tao

摘要 Abstract PDF Pages: 2356-2362

NOK与p-GSK3β(Tyr216)在非小细胞肺癌中的表达及临床意义
Expression and its clinical signiﬁcance of NOK and p-GSK3β (Tyr216) in non-small cell lung cancer

黄曌, 赵晋波, 卢强, 张志培, 赖远阳, 李维妙, 张晨曦, 刘文豪, 李小飞
HUANG Zhao, ZHAO Jinbo, LU Qiang, ZHANG Zhipei, LAI Yuanyang, LI Weimiao, ZHANG Chenxi, LIU Wenhao, LI Xiaofei

摘要 Abstract PDF Pages: 2363-2370

miR-99a在原发性肝癌组织中的表达及临床意义
Expression of miR-99a in hepatocellular carcinoma and its clinical significance

石小康, 丁佑铭, 汪斌, 余斌, 徐雨, 熊豪
SHI Xiaokang, DING Youming, WANG Bin, YU Bin, XU Yu, XIONG Hao

摘要 Abstract PDF Pages: 2371-2379

Micro146b在甲状腺乳头状癌中的表达及其对甲状腺乳头状癌侵袭迁移的影响
Expression of miR-146b in thyroid cancer and its role in invasion and migration of thyroid cancer cells

龚麒麟, 叶钦, 刘辉
GONG Qilin, YE Qin, LIU Hui

摘要 Abstract PDF Pages: 2380-2386

单纯和混合型乳腺黏液癌的临床病理特征比较
Comparison of the clinical and pathological characteristics between pure mucinous breast carcinoma and mixed mucinous breast carcinomas

高蓉梅, 彭凤翔, 陈竹, 谢丽娟
GAO Rongmei, PENG Fengxiang, CHEN Zhu, XIE Lijuan

摘要 Abstract PDF Pages: 2387-2393

96例噬血细胞综合征儿童外周血CD4⁺T细胞亚群、淋巴细胞亚群分析
Analysis of peripheral blood CD4⁺T lymphocyte subsets and lymphocyte subsets in 96 children with hemophagocytic syndrome

高海丽, 刘炜, 田亮
GAO Haili, LIU Wei, TIAN Liang

摘要 Abstract PDF Pages: 2394-2400

腹腔镜卵巢囊肿剔除术对卵巢囊肿患者卵巢功能、血清抗苗勒管激素、抑制素B的影响及其意义
Effect of LOCR on ovarian function, serum AMH and INHB in patients with ovarian cyst and its significance

施佳艳, 陈鹃, 陈琪珍
SHI Jiayan, CHEN Juan, CHEN Qizhen

摘要 Abstract PDF Pages: 2401-2406

纳布啡或芬太尼联合丙泊酚麻醉用于内镜超声检查术麻醉效果的比较
Comparison of anesthetic effects of nalbuphine or fentanyl combined with propofol for endoscopic ultrasonography

郭培培, 金朝, 李心怡, 张宗泽, 赵秋, 吴会生
GUO Peipei, JIN Zhao, LI Xinyi, ZHANG Zongze, ZHAO Qiu, WU Huisheng

摘要 Abstract PDF Pages: 2407-2411

右美托咪定术中镇静Narcotrend值与警觉/镇静评分相关性
Correlation of Narcotrend and observer’s assessment of alertness/sedation scale in monitoring dexmedetomidine sedation

陈碧芸, 刘吉平, 何菁
CHEN Biyun, LIU Jiping, HE Jing

摘要 Abstract PDF Pages: 2412-2417

不同病因肝内胆管癌行肝切除术预后与年龄的关系
Relationship between age and outcome of intrahepatic cholangiocarcinoma of different causative factors

李昊昱, 陆丽华, 夏勇, 沈锋, 李俊
LI Haoyu, LU Lihua, XIA Yong, SHEN Feng, LI Jun

摘要 Abstract PDF Pages: 2418-2424

不同X线分型食管鳞癌患者p53基因的表达与放疗敏感性的关系
Relationship between radio-therapeutic sensitivity and p53 gene expression in esophageal squamous cell carcinoma

史雪飞, 史海, 吴建峰, 朱国民, 陈胜东, 盛卫东, 王达飞
SHI Xuefei, SHI Hai, WU Jianfeng, ZHU Guomin, CHEN Shengdong, SHENG Weidong, WANG Dafei

摘要 Abstract PDF Pages: 2425-2431

分娩镇痛下第二产程剖宫产及产钳术145例分析
Analysis of 145 cases of cesarean section and forceps midwifery during the second stage of labor under labor analgesia

蹇文艳, 姚若进
JIAN Wenyan, YAO Ruojin

摘要 Abstract PDF Pages: 2432-2436

内蒙古及河北地区2型糖尿病患者勃起功能障碍的患病率
Prevalence of erectile dysfunction in patients with type 2 diabetes mellitus in Inner Mongolia and Hebei

段立志, 刘波, 张何英, 尚国爱, 赵海霞
DUAN Lizhi, LIU Bo, ZHANG Heying, SHANG Guoai, ZHAO Haixia

摘要 Abstract PDF Pages: 2437-2443

经尿道前列腺双极等离子电切术和前列腺电切术治疗良性前列腺增生的效果
Efficacy of transurethral bipolar plasma resection of prostate and transurethral resection of prostate in the treatment of benign prostatic hyperplasia

夏宗禹, 王琴, 刘胜
XIA Zongyu, WANG Qin, LIU Sheng

摘要 Abstract PDF Pages: 2444-2450

高剂量生长抑素对急诊肝硬化合并食管胃底静脉曲张破裂出血的疗效增益价值
Therapeutic value of high-dose somatostatin in the treatment of acute cirrhosis complicated with esophageal and gastric varices bleeding

夏于新, 罗雄, 牛红霞, 褚晓雯, 陈士轩
XIA Yuxin, LUO Xiong, NIU Hongxia, ZHU Xiaowen, CHEN Shixuan

摘要 Abstract PDF Pages: 2451-2456

宫颈液基细胞学联合高危型HPV E6/E7 mRNA检测在宫颈病变筛查中的应用
Application of cervical thinprep cytologic test combined with high-risk HPV E6/E7 mRNA detection in the screening of cervical lesions

林茂华, 谢芳, 毛瑛玉, 吴秋珍, 翁秀清, 陈灼英
LIN Maohua, XIE Fang, MAO Yingyu, WU Qiuzhen, WENG Xiuqing, CHEN Zhuoying

摘要 Abstract PDF Pages: 2457-2461

人工全髋关节置换术治疗成人股骨颈骨折内固定术后股骨头坏死
Total hip arthroplasty for osteonecrosis of the femoral head after internal fixation of femoral neck fracture in adults

李怀木, 方玮, 韩雪昆, 高贤, 徐兴全
LI Huaimu, FANG Wei, HAN Xuekun, GAO Xian, XU Xingquan

摘要 Abstract PDF Pages: 2462-2466

骨化醇治疗对绝经后骨质疏松妇女血清硬化素及成纤维细胞生长因子23水平的影响
Effect of calcitriol on serum levels of sclerotin and FGF23 in postmenopausal women with osteoporosis

周士进, 徐毅
ZHOU Shijin, XU Yi

摘要 Abstract PDF Pages: 2467-2471

硒对百草枯中毒患者肺纤维化的影响
Clinical study on the effect of selenium on pulmonary fibrosis in patients with paraquat poisoning

邹振武, 李德忠, 王齐兵
ZOU Zhenwu, LI Dezhong, WANG Qibing

摘要 Abstract PDF Pages: 2472-2477

血浆内毒素与重症医学科细菌感染患者的关系
Relationship between plasma endotoxin and patients with bacterial infection in intensive care unit

刘超
LIU Chao

摘要 Abstract PDF Pages: 2478-2482

儿童细菌性脓毒症中富含组氨酸糖蛋白血浆浓度及其诊断价值
Plasmic concentration of histidine-rich glycoprotein in pediatric bacterial sepsis and its diagnosis value

徐莎, 肖俊
XU Sha, XIAO Jun

摘要 Abstract PDF Pages: 2483-2487

马斯洛需要层次论理念的应用对急性心肌梗死患者行经皮冠状动脉介入手术后服药依从性、心理状态及心功能的影响
Effect of application of Maslow’s hierarchy of needs on the medication compliance, psychological state and cardiac function of patients with acute myocardial infarction undergoing percutaneous coronary intervention

席小红, 唐金凤, 李琪
XI Xiaohong, TANG Jinfeng, LI Qi

摘要 Abstract PDF Pages: 2488-2495

截瘫步行器Walkabout与ARGO对脊髓损伤患者平衡及日常生活能力的干预效果
Effect of Paraplegia Walker Walkabout and Argo on balance and daily living ability of patients with spinal cord injury

吴金玲, 杜宁, 石秀秀, 唐金树
WU Jinling, DU Ning, SHI Xiuxiu, TANG Jinshu

摘要 Abstract PDF Pages: 2496-2500

快速康复护理在腹腔镜下患侧输卵管开窗妊娠病灶清除术治疗异位妊娠患者中的应用
Application of rapid rehabilitation nursing in laparoscopic focal clearance and fenestration for affected side fallopian tube in treatment of ectopic pregnancy patients

卢宗君, 吴海葵, 吴先群
LU Zongjun, WU Haikui, WU Xianqun

摘要 Abstract PDF Pages: 2501-2506

护理风险管理对下肢动脉粥样硬化性闭塞症患者介入术后对比剂肾病发生率的影响
Effects of nursing risk management on incidence rate of contrast-induced nephropathy after interventional operation in patients with lower extremity atherosclerotic occlusive disease

韦小妹, 谢艳
WEI Xiaomei, XIE Yan

摘要 Abstract PDF Pages: 2507-2513

综述 Review

骨微环境在恶性肿瘤骨转移中的作用及进展
Role and progression of bone microenvironment in the development of bone metastasis in malignant tumors

马晓婷, 俞静
MA Xiaoting, YU Jing

摘要 Abstract PDF Pages: 2514-2518

宫颈癌根治术后盆底功能变化及康复治疗研究进展
Research progress on changes of pelvic floor function and rehabilitation after radical hysterectomy

卓佳慧, 夏志军
ZHUO Jiahui, XIA Zhijun

摘要 Abstract PDF Pages: 2538-2543

痤疮后凹陷性瘢痕治疗的研究进展
Research progress in treatment of acne atrophic scar

王艺潭, 栗玉珍
WANG Yitan, LI Yuzhen

摘要 Abstract PDF Pages: 2544-2548

个案管理模式在慢性心力衰竭患者中应用的研究进展
Research progress of case management model in patients with chronic heart failure

张丽, 崔德君, 王娟娟, 田梅梅
ZHANG Li, CUI Dejun, WANG Juanjuan, TIAN Meimei

摘要 Abstract PDF Pages: 2549-2553

临床病例讨论 Case Report

2例伴有假腺样结构的黏液样肾上腺皮质腺瘤临床病理观察
Clinicopathological characteristics of myxoid adrenocortical adenoma with a pseudoglandular pattern: An analysis of 2 cases

赵丽娜, 袁静萍, 曾智, 余鑫鑫, 刘琳
ZHAO Lina, YUAN Jingping, ZENG Zhi, YU Xinxin, LIU Lin

摘要 Abstract PDF Pages: 2554-2559

多处COL4A4基因突变薄基底膜肾病1例并文献复习
Thin basement membrane nephropathy with multiple COL4A4 gene mutations: A case report and literature review

刘玉洁, 张书锋, 刘翠华
LIU Yujie, ZHANG Shufeng, LIU Cuihua

摘要 Abstract PDF Pages: 2560-2564

1例非小细胞肺癌软脑膜转移伴昏迷患者临床病理分析
Clinicopathological analysis of leptomeningeal metastasis with coma in patients with non-small cell lung cancer: A case report

蔡婧, 魏建平, 刘安文
CAI Jing, WEI Jianping, LIU Anwen

摘要 Abstract PDF Pages: 2579-2586

异时性多原发恶性肿瘤1例临床病理分析并文献复习
Multiple primary malignant tumors: A case report of clinicopathological analysis and literature review

朱涤潮, 张晔, 夏郁金, 金雷, 张明辉, 张涛, 徐光如
ZHU Dichao, ZHANG Ye, XIA Yujin, JIN Lei, ZHANG Minghui, ZHANG Tao, XU Guangru

摘要 Abstract PDF Pages: 2587-2595

1例晚期EGFR阳性非小细胞肺癌的联合治疗
Combination therapy in the treatment of advanced EGFR-mutated non-small cell lung cancer: A case report

钱洁, 黄艾弥, 王韡旻, 顾爱琴
QIAN Jie, HUANG Aimi, WANG Weimin, GU Aiqin

摘要 Abstract PDF Pages: 2616-2621

1例EGFR野生型肺腺癌的靶向治疗
Targeted therapy for EGFR wild-type lung adenocarcinoma: A case report

刘斌, 黄彭, 刘双柏, 梁彦超, 谢波
LIU Bin, HUANG Peng, LIU Shuangbo, LIANG Yanchao, XIE Bo

摘要 Abstract PDF Pages: 2622-2626

1例晚期肺鳞癌患者EGFR突变病例报道并文献复习
EGFR mutations in patients with advanced lung squamous cell carcinoma: A case report and literature review

周海英, 韩进伟, 吕铮, 吴爱萍
ZHOU Haiying, HAN Jinwei, LÜ Zheng, WU Aiping

摘要 Abstract PDF Pages: 2627-2630

驱动基因阳性的晚期肺腺癌精准治疗1例
Precision treatment of advanced lung adenocarcinoma with driver gene positive: A case report

张倩云, 李鑫, 杨邵瑜, 陈雪琴
ZHANG Qianyun, LI Xin, YANG Shaoyu, CHEN Xueqin

摘要 Abstract PDF Pages: 2631-2634