Objective: To explore the effect of paraplegic walker on the recovery of balance function and activities of daily living in patients with spinal cord injury. Methods: From October 2015 to October 2018, 40 patients with complete thoracolumbar spinal cord injury were randomly divided into an observation group and a control group, with 20 cases in each group. All patients were equipped with paraplegic walking device. The control group was treated with ARGO paraplegic walking device, while the observation group was treated with Walkabout paraplegic walking device. Before the treatment and 3 months after the treatment, the balance function and activities of daily living of the two groups wearing paraplegic walkers were compared. Results: Three months after wearing paraplegic walking, the scores of Berg Balance Scale (BBS) and Modified Bathel Index (MBI) Scale in both groups were higher than those before wearing paraplegia walking, and the scores of each group were significantly higher than those before wearing paraplegia walking (P<0.05). There was significant difference between the observation group and the control group (P<0.05). Conclusion: Walkabout walking device can effectively assist paraplegic patients to walk, can significantly improve the balance function and activities of daily life of patients, and their quality of life, it is worthy of clinical application.