文章摘要

肉芽肿性多血管炎支气管改变1例及文献复习

作者: 1徐佳欢, 1王新年, 1黄新, 2霍云龙, 1赵立, 1徐小嫚
1 中国医科大学附属盛京医院呼吸与危重症医学科，沈阳 110004
2 中国医科大学附属盛京医院病理科，沈阳 110004
通讯: 徐小嫚 Email: xuxm@sj-hospital.org
DOI: 10.3978/j.issn.2095-6959.2020.06.047

摘要

肉芽肿性多血管炎(granulomatosis with polyangiitis，GPA)是一种系统性自身免疫性疾病，任何器官均可受累，呼吸道、肺及肾累及较常见。过去GPA被认为是一种罕见疾病，但近些年来，越来越多的GPA病例被报道，GPA的诊治不容忽视。本文报道1例伴双肺多发结节、空洞伴有支气管血管束增粗的GPA病例及复习相关文献，希望在临床疾病诊断中提供参考价值。当影像学表现存在支气管壁增厚、狭窄，以及抗感染效果不佳的情况下，需注意有GPA可能性。
关键词： 抗中性粒细胞细胞质抗体；相关性血管炎；肉芽肿性多血管炎；气道改变

Bronchial changes in granulomatosis with polyangiitis: A case report and literature review

Authors: 1XU Jiahuan, 1WANG Xinnian, 1HUANG Xin, 2HUO Yunlong, 1ZHAO Li, 1XU Xiaoman
1 Department of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang 110004, China
2 Department of Pathology, Shengjing Hospital of China Medical University, Shenyang 110004, China

CorrespondingAuthor: XU Xiaoman Email: xuxm@sj-hospital.org

DOI: 10.3978/j.issn.2095-6959.2020.06.047

Abstract

Granulomatosis with polyangiitis (GPA) is a systemic autoimmune disease, involving any organ, respiratory tract, lung and kidney. In the past, GPA was considered a rare disease, but in recent years, more and more cases of GPA have been reported, the diagnosis and treatment of GPA cannot be ignored. This paper reports a case of GPA with multiple pulmonary nodules, voids and enlargement of bronchovascular bundles and reviews the relevant literature. It is hoped that this study can provide reference for the diagnosis of clinical diseases. When imaging manifestations of bronchial wall thickening, stenosis, and poor anti-infective effect, attention should be paid to the possibility of GPA.
Keywords： antineutrophil cytoplasmic autoantibody; associated vasculitis; granulomatosis with polyangiitis; airway changes

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