二氢杨梅素与糖尿病肾病的研究进展
| 作者: |
1吕慧婕,
1许拓,
1何剑琴,
1杨丝丝,
2奉水东,
1凌宏艳
1 南华大学生理学教研室，湖南 衡阳 421000 2 南华大学社会医学与卫生管理教研室，湖南 衡阳 421000 |
| 通讯: |
凌宏艳
Email: linghongyan0203@126.com |
| DOI: | 10.3978/j.issn.2095-6959.2018.10.029 |
| 基金: | 湖南省自然科学基金 (2018JJ2347)；湖南教育厅基金 (16C1411)；衡阳市科技局基金 (2016KJ64)。 |
摘要
二氢杨梅素(dihydromyricetin，DHM)是一种葡萄科属的植物，主要活性成分是黄酮类化合物。黄酮类化合物在藤茶中含量丰富，又称长寿藤，因是蛇葡萄科植物的提取物，所以又将其称为蛇葡萄素。近年来，DHM具有的降血糖、抗氧化、抗炎、抗肿瘤及护肝等作用已被科学家们用多种方式证实。其中一些研究证明DHM在糖尿病肾病的发生发展过程中也发挥一定的作用，但其具体机制还未完全阐述清楚。
关键词：
二氢杨梅素；糖尿病肾病；中药
Progress of dihydromyricetin in diabetic nephropathy
CorrespondingAuthor: LING Hongyan Email: linghongyan0203@126.com
DOI: 10.3978/j.issn.2095-6959.2018.10.029
Foundation: This work was supported by the Natural Science Foundation of Hunan Province (2018JJ2347), Educational Bureau of Hunan Province (16C1411) and Science Technology Department of Hengyang (2016KJ64)
Abstract
Dihydromyricetin (DHM) is a genus of the genus Vitis. The main active ingredient is flavonoids. It is rich in vine tea, also known as longevity vine. Because it is an extract of the snake grape family, it is It is called snake vine. In recent years, DHM has been used by scientists to confirm blood sugar, anti-oxidation, anti-inflammatory, anti-tumor and liver protection. Some studies have shown that dihydromyricetin also plays a certain role in the development of diabetic nephropathy, but its specific mechanism has not been fully elucidated. This article reviews the biological characteristics of dihydromyricetin and its recent research progress in the treatment of diabetic nephropathy, and provides new ideas for the treatment of patients.
Keywords：
dihydromyricetin; diabetic nephropathy; Chinese herb