Objective: To study the cytological features of thyroid papillary carcinoma associated with Hashimoto disease. Methods: Retrospective analysis of 14 cases of thyroid papillary carcinoma associated with Hashimoto disease confirmed by postoperative histopathology were investigated with the method of fine needle aspiration cytology (FNAC). Relevant literatures were reviewed. Discussion was focused on the diagnosis and differential diagnosis of this kind of disease compared with histopathology and clinical data. Results: Based on the FNAC findings, 14 patients underwent surgery. The final pathology was consistent with the FNAC findings. The microscopically morphology of this disease was abundant in cells. The cytological characteristics of thyroid papillary carcinoma associated with Hashimoto disease included papillary carcinoma and eosinocyte with interstitial infiltration of large number of lymphocytes, plasma cells and histiocyte cells. Neuronal intranuclear inclusions were visible within the tumour cells. Conclusion: Thyroid papillary carcinoma associated with Hashimoto disease has a relatively unique cytological feature included papillary carcinoma, nuclear sulcus and neuronal intranuclear inclusions with interstitial infiltration of large number of lymphocytes, plasma cells, and histiocyte cells. FNAC is an extremely useful tool in the management of this disease preoperatively.