Objective: To explore the clinicopathologic characteristics and histopathological diagnosis of bladder pheochromocytoma. Methods: A total of 14 cases of bladder pheochromocytoma were retrospectively retrieved from the surgical pathology files of Peking Union Medical College Hospital. The clinical and pathological findings were analyzed with a review of the literature. Results: Of the 14 patients with bladder pheochromocytoma, eight were males and six were females. The median age was 46.7 years (ranged from 14 to 63), and the median maximum diameter of the tumors was 2.5 cm (ranged from 0.2 to 8). Microscopic examination showed that the tumor cells were polygonal to spindle-shaped arranged into trabecular, solid or zellballen pattern in a rich vascular network. The tumor was typically not well circumscribed with infiltration of bladder wall. Immunohistochemical staining showed that CgA and Syn were positive for tumor cells, and S-100 was positive for the spindle cells around tumor nests. AE1/AE3 was typically negative. Ki-67 index ranged from 1% to 10%. Nine cases received transurethral resection of bladder tumor, 4 cases of which had local recurrence. Five cases used bladder resection, 2 cases of which had local recurrence. Conclusion: Pheochromocytoma is a rare tumor of the bladder, and the pathological diagnosis is based on morphological and immunohistochemical characteristics. Local recurrence following tumor resection is common, while metastasis is rare.