1例气球细胞痣临床及病理分析
作者: |
1王露,
1司海鹏,
1章宜芬
1 江苏省中医院病理科,南京 210000 |
通讯: |
章宜芬
Email: sea_sky_way@163.com |
DOI: | 10.3978/j.issn.2095-6959.2016.12.037 |
摘要
目的:学习气球细胞痣的临床病理诊断及鉴别诊断。方法:对1例气球细胞痣进行临床资料、病理形态及免疫组织化学观察,并结合文献对其诊断及鉴别诊断进行学习。结果:前胸壁皮肤先天性色素痣,近1年来增大,其组织学上表现为混合痣伴多量细胞胞浆丰富,呈气球样。免疫组织化学标记气球样细胞Melan A、S100、HMB45阳性,CD68阴性。结论:气球细胞痣是较为罕见的一种黑素细胞痣,根据其临床及组织学特征,结合免疫组织化学方法,有助于其诊断及鉴别诊断。
关键词:
气球细胞痣
病理诊断
鉴别诊断
免疫组织化学
Clinicopathological analysis of one case of the balloon cell nevus
CorrespondingAuthor: ZHANG Yifen Email: sea_sky_way@163.com
DOI: 10.3978/j.issn.2095-6959.2016.12.037
Abstract
Objective: To study the pathological diagnosis and differential diagnosis of the balloon cell nevus (BCN). Methods: The clinical data, pathological and immunohistochemical studies of one case of balloon cell nevus were organized. And then we learned its pathological diagnosis and differential diagnosis combined with literature. Results: The congenital nevus on the skin of the chest wall was getting bigger in the past year. The performance of its histology looked as compound nevi with a large number of rich ballooning cytoplasm. The Melan A, S100, HMB45 was positive, CD68 was negative in the balloon-like cells by using immunohistochemistry. Conclusion: Balloon cell nevus is a kind of rarely melanocytic nevi. The clinical and histological features combined with immunohistochemistry of BCN can contribute to its pathological and differential diagnosis.