Objective: To explore the clinical value of multi-slice CT (MSCT) in the diagnosis of peroneal tendon dislocation accompanying intra-articular calcaneal fractures. Methods: One hundred and forty-two patients with intra-articular calcaneal fractures, a total of 154 feet in patients admitted to Traditional Chinese Medicine Hospital of Xinle from January, 2013 to June, 2013 underwent MSCT scanning, carried out the volume virtual reality (VR) and multi planar reconstruction (MPR) of supplementary tendons, and the calcaneal width of posterior edge of sustentaculum and the width of the tuberosity posterior to the sustentaculum in calcaneal fractures were measured. Results: One hundred and twenty-eight feet without peroneal tendons dislocation (group without dislocation), axial position and coronal position in MPR and VR diagram showed that the peroneal tendons were located in the peroneal tendons groove; Peroneal tendons displacement was in 26 cases (dislocation group), MSCT showed that peroneal tendons were out of peroneal tendons groove, and lateral displacement. The width of posterior edge of sustentaculum and tuberosity posterior to the sustentaculum in calcaneal fractures of the dislocation group was greater than that of the group without dislocation [(5.08±0.61) vs. (4.78±0.59) cm, (4.18±0.47) vs. (3.83±0.50) cm, P<0.05]. The dislocation group underwent open reduction and steel plate internal fixation, and peroneal tendons dislocation was not to deal with. Fifteen feet were followed up for 12 months after operation, three feet with dislocated peroneal tendons were back to the normal location, and 12 feet were still in dislocation. Conclusion: The multi-angle peroneal tendons and the location of the peroneal tendons ditch can be observed by MSCT, and it has an accurate judgment in the intra-articular calcaneal fractures fibula tendon dislocation or not, so it has a great significance in clinical diagnosis and treatment of dislocation of the peroneal tendons.