肠道菌群与非酒精性脂肪肝病相关性研究进展
| 作者: |
1蒋李妍,
1肖新华
1 南华大学附属第一医院内分泌科，湖南 衡阳 421001 |
| 通讯: |
肖新华
Email: xiaoxinhua139@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2016.12.031 |
| 基金: | 教育部留学人员归国基金, 2013JYB03 国家自然科学基金, 81270925 |
摘要
非酒精性脂肪性肝病(non-alcoholic fatty liver disease，NAFLD)发病机制尚未完全阐明，目前广为接受的是“二次打击”学说，近年来关于肠道菌群与NAFLD的研究不断深入，充实和发展了“二次打击”学说，也为NAFLD的治疗提供了新思路。本文就肠道菌群与NAFLD相关性的研究进展及益生元、益生菌治疗NAFLD进展进行综述。
关键词：
肠道菌群
非酒精性脂肪肝病
益生元
益生菌
Research progress on correlation between gut microbiota and non-alcoholic fatty liver disease
CorrespondingAuthor: XIAO Xinhua Email: xiaoxinhua139@163.com
DOI: 10.3978/j.issn.2095-6959.2016.12.031
Abstract
The pathogenesis of non-alcoholic fatty liver disease (NAFLD) has not been fully illustrated. The “two hits” theory is now widely accepted. In recent years, the research on gut microbiota and NAFLD is deepening, which enriched and developed the theory of “two hits”, thus providing new ideas for the treatment of NAFLD. In this review, the research progress on correlation between gut microbiota and NAFLD, as well as the role of prebiotics and probiotics in the treatment of NAFLD were summarized.