消化道淋巴瘤的临床分析
| 作者: |
1严安芝,
1徐杨
1 中南大学湘雅二医院消化内科，长沙 410011 |
| 通讯: |
徐杨
Email: happyxuyang2013@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2016.10.002 |
摘要
目的：探讨消化道淋巴瘤(primary gastrointestinal lymphoma，PGIL)的临床特征。方法：回顾性分析中南大学湘雅二医院2011年至2015年收治的经病理证实为PGIL患者的临床资料。结果：本研究中男性9例，占69.2%，女性4例，占30.8%，41~50岁年龄段的患者6例，占46.1%；临床表现以非特异性的消化道症状为主，其中腹痛10例，占77%，腹胀3例，占23.1%，腹泻3例，占23.1%，恶心呕吐4例，占30.8%，黑便或便血4例，占30.8%，呕血1例，占7.7%，食欲下降1例，占7.7%；病理证实均为非霍奇金淋巴瘤，其中黏膜相关淋巴组织(mucosa-associated lymphoid tissue，MALT)淋巴瘤3例，占23.1%，弥漫大B细胞淋巴瘤(diffuse large B cell lymphoma，DLBCL)6例，占46.1%，肠病相关性T细胞淋巴瘤(enteropathy-associated T-cell lymphoma，EATL)3例，占23.1%，结外NK/T细胞淋巴瘤(extranodal natural/killer T-cell lymphoma，ENKTL)1例，占7.7%。结论：PGIL好发于中老年男性患者，临床表现以腹痛最常见，病理类型以DLBCL为主，消化内镜及CT检查有助于PGIL的诊断。
关键词：
消化道淋巴瘤
消化内镜
CT
超声内镜
Clinical analysis of primary gastrointestinal lymphoma
CorrespondingAuthor: XU Yang Email: happyxuyang2013@163.com
DOI: 10.3978/j.issn.2095-6959.2016.10.002
Abstract
Objective: To investigate the clinical characteristic of patients with primary gastrointestinal lymphoma (PGIL). Methods: Retrospective reviewed the clinical data of 13 patients diagnosed with PGIL in the digestive internal medicine of Xiangya Second Hospital of Central South University from January 2011 to August 2015. Results: In this study, 9 cases are male, accounting for 69.2%, 4 cases are female, accounting for 30.8%, and 6 cases of patients were in the age of 41~50 years old, accounting for 46.1%; these cases were mainly with non-specific gastrointestinal symptoms, including 10 cases of abdominal pain (77%), 3 cases of abdominal distension (23.1%), 3 cases of diarrhea, accounting for 23.1%, 3 cases of diarrhea (23.1%), 4 cases of black or bloody, (30.8%), 1 case of hematemesis (7.7%), 1 case of male-appetite (7.7%); the pathology are non-Hodgkin’s lymphoma, including 3 cases of mucosa-associated lymphoid tissue (MALT) lymphoma (23.1%), 6 cases of diffuse large B cell lymphoma (DLBCL) (46.1%), 3 cases of enteropathy-associated T-cell lymphoma (EATL) (23.1%), 1 cases of extranodal natural/killer T-cell lymphoma (ENKTL) (7.7%). Conclusion: PGIL more likely occurs in old man, and the most common symptom and pathological type are abdominal pain and DLBCL, respectively. Endoscopy and CT examination is useful to diagnosis.