Objective: To study the influence of cesarean delivery women’s mood and quality life by the problem oriented health education. Methods: 80 cases of plane palace women were randomly divided into observation group and control group by random number table method, which including 40 cases in each of group. Control group using conventional health education, nursing routine asked for patients treated in plane palace knowledge education and care; observation group adopts the model of problem oriented health education intervention. Results: By means of plane place of women’s education during the hospitalization and every month’s return visit of the patients with 6 months of discharge, observing the patients’ metrics from treatment adherence and initiative, the healthy index, life satisfaction, emotional score. The treatment adherence and enthusiasm of the observation group patients is superior to control group, the difference has statistical significance (P<0.05); Observation group of patients health indices, life satisfaction and emotional score was better than control group, the difference has statistical significance (P<0.05); Observe the emotional state of patients was superior to that of the control group, the difference is statistically significant (P<0.05). Conclusion: Using PBL education mode could stimulate the subjective initiative of patients to disease related knowledge learning and reduce the generation of negative emotions and improve the quality of life.