卵巢无性细胞瘤临床病理分析并文献复习
| 作者: |
1吴永芳,
1许春伟,
1邵云,
1王海艳,
1崔淼,
1张俊,
1张博,
1李晓兵
1 军事医学科学院附属医院病理科，北京 100071 |
| 通讯: |
吴永芳
Email: wwyff7950385@163.com 张博 Email: zenwo@qq.com |
| DOI: | 10.3978/j.issn.2095-6959.2015.08.030 |
摘要
目的：探讨卵巢无性细胞瘤的临床病理学特点及诊断要点。方法：对2例无性细胞瘤进行临床资料、病理形态学及免疫组化观察，并结合文献对其诊断及鉴别诊断进行探讨。结果：镜下肿瘤细胞被窄的纤维组织分隔呈巢状、岛屿状、条索状，纤维隔内有多少不等的淋巴细胞浸润，瘤细胞与核的大小外观呈明显一致性，胞质丰富淡染，核大圆形，核仁明显，核分裂像易见。免疫组化示肿瘤细胞PLAP呈不同程度阳性。结论：掌握无性细胞瘤的病理特点，提高对无性细胞瘤的认识，对避免误诊是至关重要的。
关键词：
无性细胞瘤
卵巢
病理学
临床
免疫组化
Clinicopathological features of ovarian dysgerminoma and literature review
CorrespondingAuthor: WU Yongfang Email: wwyff7950385@163.com
DOI: 10.3978/j.issn.2095-6959.2015.08.030
Abstract
Objective: To investigate and discuss the clinicopathological features, diagnosis of ovarian dysgerminoma. Methods: By analysis the features of clinicopathology and immunohistochemistry of 2 cases, and combining together the review of the literatures. Results: The microscopic tumor cell nests can be separated by narrow fibrous tissue, islands, funicular, fibre separated with varying amounts of lymphocyte infiltration, the obvious appearance of the size of the tumor cells and nuclear is consistency, cytoplasmic rich light dye, nuclear big round, obvious nucleoli, nuclear fission as easy to see. Positive immunohistochemical PLAP show varying degrees of tumor cells. Conclusion: It is essential to grasp the pathological characteristics of ovarian dysgerminoma and enhance awareness so as to avoid misdiagnosis.