稳定期COPD患者夜间低氧血症的筛查及氧疗干预的临床研究
| 作者: |
1徐栋辉
1 上海市复旦大学附属中山医院青浦分院呼吸内科，上海 201700 |
| 通讯: |
徐栋辉
Email: xudrmarch@aliyun.com |
| DOI: | 10.3978/j.issn.2095-6959.2015.02.019 |
摘要
目的：筛查稳定期慢性阻塞性肺病(chronic obstructive pulmonary disease，COPD)患者夜间血氧情 况，对其中部分夜间低氧血症患者行氧疗干预并观察疗效。方法：符合条件的患者126例，随机 分为2组，氧疗组60例，对照组66例，氧疗组行长期家庭氧疗(long-term oxygen therapy，LTOT)干 预，观察急性发作次数和住院次数，肺功能，动脉血气分析情况，随访2年，记录数据，对照组未 行干预。结果：氧疗组患者急性发作次数，肺功能，动脉血气分析情况得到明显改善(P<0.05)，对 照组无明显变化。结论：稳定期COPD患者夜间低氧血症的发生率为31.5%，实行氧疗干预后，患 者生活质量得到提高，精神负担得到减轻，有益于家庭、社会的稳定和谐。
关键词：
稳定期COPD
低氧血症
氧疗干预
Clinical study on screening of COPD patients on stable stage with nocturnal hypoxemia and oxygen therapy intervention
CorrespondingAuthor: XU Donghui Email: xudrmarch@aliyun.com
DOI: 10.3978/j.issn.2095-6959.2015.02.019
Abstract
Objective: Screening nocturnal oxygen saturation in COPD patients on stable stage, some of which with nocturnal hypoxemia were treated with oxygen therapy intervention and observed curative effect. Methods: Consistent with the conditions of 126 patients were randomly divided into 2 groups, 60 cases in oxygen therapy group, 66 cases in control group. Group of oxygen therapy was intervened for long-term home oxygen therapy (long-term oxygen therapy, LTOT), times of acute episodes and hospitalizations, pulmonary function, arterial blood gas analysis were observed for 2 years, and recorded the data, the control group was without intervention. Results: Times of acute episodes, pulmonary function, arterial blood gas analysis of patients in oxygen therapy group were significantly improved (P<0.05), the control group had no obvious change. Conclusion: Occurrence rate of COPD patients on stable stage with nocturnal hypoxemia was 31.5%. After the intervention of oxygen therapy, the quality of life of the patients were improved, mental burden eased, and were beneficial to the family and social stability and harmony.