红细胞分布宽度与高血压相关性的研究进展
| 作者: |
1马文,
1匡泽民,
1陆瑶,
2刘星,
1袁洪
1 中南大学湘雅三医院心内科，湖南省高血压研究中心，长沙 410013 2 中南大学湘雅三医院心内科，湖南省高血压研究中心，长沙 410013，袁洪 |
| 通讯: |
袁洪
Email: yuanhong1975@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2013.03.011 |
摘要
红细胞分布宽度（red cell distribution width，RDW）是通过定量的方法反映循环中红细胞大小变异性的指标。近期较多研究发现RDW的升高能够作为预测人群心血管疾病预后不良的指标，即使RDW值在正常参考值范围内，处于高值的人群存在更高的心血管疾病死亡风险。本文综述了RDW与高血压发病、血压水平、血压形态及靶器官损害之间的关系，并探讨了RDW升高提示高血压预后不良的机制。由于RDW简单易得，可以作为高血压患者预后风险评估有潜力的指标。
关键词：
红细胞分布宽度；高血压；靶器官损害；炎症；氧化应激
Research progress in correlation between red blood distribution width and hypertension
CorrespondingAuthor: YUAN Hong Email: yuanhong1975@163.com
DOI: 10.3978/j.issn.2095-6959.2013.03.011
Abstract
Red cell distribution width (RDW) is a quantitative indicator for red blood cell size variability in blood circulation. Recent studies have shown that high RDW, even within the normal range, is associated with high morbidity and mortality in patients with cardiovascular disease (CVD). This paper reviewed the relationship between RDW and hypertension, as well as the underlying mechanisms. RDW, which is easy to get, can serve as potential indicators to predict the prognosis of patients with hypertension.