江苏省泰兴市农村地区结直肠癌危险因素的病例对照家系研究
| 作者: |
1李雪兰
1 泰兴市第二人民医院内科，江苏 泰兴 225411 |
| 通讯: |
李雪兰
Email: 2415180097@qq.com |
| DOI: | 10.3978/j.issn.2095-6959.2013.02.004 |
摘要
目的：探讨江苏省泰兴市农村地区结直肠癌发生的危险因素。方法：确定结直肠癌病例家系和对照家系
各152 户，每组456 人，以家庭为单位进行入户当面访谈的方式收集人群资料。应用单因素和多因素非条件性logistic
回归分析探讨不同因素，尤其是环境因素对结直肠癌发病的影响。结果：腹部不适症状、高脂、高蛋白饮食、饮酒
和肥胖等因素在病例家系与对照家系的分布中差异具有统计学意义。结论：腹部不适症状、高脂、高蛋白饮食、饮
酒和肥胖等因素是病例家系成员发生结直肠癌的危险因素。
关键词：
结直肠癌；病例对照；危险因素；家系分析
各152 户，每组456 人，以家庭为单位进行入户当面访谈的方式收集人群资料。应用单因素和多因素非条件性logistic
回归分析探讨不同因素，尤其是环境因素对结直肠癌发病的影响。结果：腹部不适症状、高脂、高蛋白饮食、饮酒
和肥胖等因素在病例家系与对照家系的分布中差异具有统计学意义。结论：腹部不适症状、高脂、高蛋白饮食、饮
酒和肥胖等因素是病例家系成员发生结直肠癌的危险因素。
A case-control family study of colorectal cancer in rural area of Taizhou City in Jiangsu Province
CorrespondingAuthor: LI Xuelan Email: 2415180097@qq.com
DOI: 10.3978/j.issn.2095-6959.2013.02.004
Abstract
Objective: To explore the risk factors of colorectal cancer in the rural area Taizhou City in Jiangsu
Province. Methods: One hundred and fifty-two families with colorectal cancer and 152 control
families (456 persons in each group) were selected from the rural area in 3 counties of Taizhou City.
A total of 912 people were surveyed and assessed using population-based case-control family study.
Results: There were significant differences in symptoms of abdominal discomfort, high-fat and
high-protein diet, drinking, and obesity between the colorectal cancer family and the control family.
Conclusion: Symptoms of abdominal discomfort, high-fat and high-protein diet, drinking, and obesity are the risk factors for colorectal cancer.
Province. Methods: One hundred and fifty-two families with colorectal cancer and 152 control
families (456 persons in each group) were selected from the rural area in 3 counties of Taizhou City.
A total of 912 people were surveyed and assessed using population-based case-control family study.
Results: There were significant differences in symptoms of abdominal discomfort, high-fat and
high-protein diet, drinking, and obesity between the colorectal cancer family and the control family.
Conclusion: Symptoms of abdominal discomfort, high-fat and high-protein diet, drinking, and obesity are the risk factors for colorectal cancer.