Objective: To explore influence of the track type of comprehensive rehabilitation nursing intervention on improvement of lung function and quality of life of the rural patients with stable chronic obstructive pulmonary disease (COPD). Methods: 70 patients with stable COPD in rural areas were randomly divided into two groups, 35 in intervention group and 35 in control group. The intervention group received tracking comprehensive rehabilitation nursing, based on the routine treatment, plus training of respiratory function, exercise, nutrition and psychology, etc., while the control group was treated with conventional therapy and self-training. The lung function, 6-minute walk distance, George Respiratory Questionnaire (SGRQ) score, patients with acute exacerbation episodes and the number of cases of hospitalization times between the two groups were compared before and after the intervention. Results: Before intervention, there were no significant difference with the lung function, 6-minute walk distance and SGRQ scores of the two groups (P>0.05); but 6 months after the intervention, the differences of the lung function and SGRQ scores of the two groups were statistically significance (P<0.05). Conclusion: Track-type comprehensive rehabilitation care can improve lung function and quality of life of rural patients with stable COPD.