文章摘要

分支动脉粥样硬化病的临床研究进展

作者: 1孙向军, 1寇桂娟, 2李战永
1 河北省廊坊市人民医院神经内科，河北 廊坊 065000
2 河北省廊坊师范学院生命科学学院，河北 廊坊 065000
通讯: 李战永 Email: lizy1537@126.com
DOI: 10.3978/j.issn.2095-6959.2016.04.030
基金: 河北省廊坊市科学技术研究与发展计划项目, 2013013008C

摘要

分支动脉粥样硬化病(branch atheromatous disease，BAD)是一种急性缺血性卒中，为颅内小血管病变，其病因与动脉粥样硬化有关。与其它脑小血管病相比，BAD更易出现病情进展加重。临床上有多种BAD分型，典型的BAD亚型有豆纹动脉BAD、脑桥旁正中动脉BAD以及脉络膜前动脉BAD。不同亚型BAD的影像学特点各异，以此可作为其临床诊断依据。多种因素与BAD的发病及进展有关，目前尚无对急性期BAD确切有效的治疗方法。与腔隙梗死相比，BAD的预后较差。
关键词： 分支动脉粥样硬化病 豆纹动脉 脑桥旁正中动脉 进行性运动障碍 危险因素

Clinical progress of branch atheromatous disease

Authors: 1SUN Xiangjun, 1KOU Guijuan, 2LI Zhanyong
1 Department of Neurology, the People’s Hospital of Langfang City, Langfang Hebei 065000
2 College of Life Science, Langfang Teachers University, Langfang Hebei 065000, China

CorrespondingAuthor: LI Zhanyong Email: lizy1537@126.com

DOI: 10.3978/j.issn.2095-6959.2016.04.030

Abstract

Branch atheromatous disease (BAD) is an intracranial small vessel disease, it has been recognized as one of the types of acute ischemic stroke and its etiology related to atherosclerosis. It often shows progressive motor deficits leading to severe disability. Representative vascular territories of BAD type infarcts are lenticulostriate artery (LSA), pontine paramedian artery (PPA) and less frequently anterior choroidal artery. The imaging features of BAD vary with those subtypes, which can be used as the basis of their clinical diagnosis. Many risk factors were associated with BAD. However, there are not any effective treatments for the acute phase of BAD currently, and BAD has poor prognosis when compared with lacunar infarction.

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