文章摘要

C-TIRADS分类方法联合超声剪切波弹性成像对甲状腺良恶性结节的诊断价值

作者: 1马磊, 1周丽霞, 1卢冬敏
1 秦皇岛市第二医院超声科,秦皇岛 河北 066600
通讯: 马磊 Email: nieyan158@163.com
DOI: 10.3978/j.issn.2095-6959.2022.11.012
基金: 秦皇岛市第二医院(201602A212)。

摘要

目的:通过与美国放射学会(American College of Radiology,ACR)-甲状腺影像报告和数据系统(Thyroid Imaging Reporting and Data System,TIRADS)对比,验证中文版TIRADS(Chinese version TIRADS,C-TIRADS)的应用价值,并进一步探讨C-TIRADS联合剪切波弹性成像(shear wave elastography,SWE)对甲状腺良恶性结节的诊断价值。方法:回顾性分析2019年1月至2021年12月在秦皇岛市第二医院进行超声检查并获得明确病理结果的90例甲状腺结节患者(90个结节),根据C-TIRADS、ACR-TIRADS分类规则,以病理结果为金标准,计算各系统各风险分层的恶性率,比较两种系统的诊断效能,并分析C-TIRADS联合SWE对甲状腺结节良恶性的诊断效能。结果:90个甲状腺结节中,良性结节43个,恶性结节47个。C-TIRADS、ACR-TIRADS的风险分层级别下的实际恶性率内部对比差异有统计学意义(P0.05),C-TIRADS敏感度低于ACR-TIRADS(78.7% vs 93.6%),特异度高于ACR-TIRADS(72.1% vs 58.1%)。C-TIRADS联合SWE诊断的敏感度为95.7%,特异度为72.1%,敏感度相比单一C-TIRADS诊断提高(P<0.05)。结论:C-TIRADS对于甲状腺结节良恶性鉴别诊断的效能与ACR-TIRAD接近,且有更高的特异度,有助于减少不必要的穿刺;同时联合SWE可进一步提高诊断效能,为临床决策提供更好的指导。
关键词: 甲状腺结节;超声;C-TIRADS指南;剪切波弹性成像;诊断

Diagnostic value of C-TIRADS classification combined with ultrasonic shear wave elastography in benign and malignant thyroid nodules

Authors: 1MA Lei, 1ZHOU Lixia, 1LU Dongmin
1 Department of Ultrasound, Qinhuangdao Second Hospital, Qinhuangdao Hebei 066000, China

CorrespondingAuthor: MA Lei Email: nieyan158@163.com

DOI: 10.3978/j.issn.2095-6959.2022.11.012

Foundation: This work was supported by the Qinhuangdao Second Hospital, China (201602A212).

Abstract

Objective: To validate the application value of Chinese version TIRADS (C-TIRADS) for thyroid nodules by comparing with the American College of Radiology (ACR) Thyroid Imaging Reporting and Data System (TIRADS), and to explore the diagnostic value of C-TIRADS combined with shear wave elastography (SWE) for benign and malignant thyroid nodules. Methods: A retrospective analysis was performed on 90 patients (90 nodules) with thyroid nodules who underwent ultrasonography and obtained clear pathological results in Qinhuangdao Second Hospital from January 2019 to December 2021. According to the classification rules of C-TIRADS and ACR-TIRADS, the malignant rate of each risk stratification in each system was calculated with pathological results as the gold standard. The diagnostic efficacy of the 2 systems was compared, and the diagnostic efficacy of C-TIRADS combined with SWE for benign and malignant thyroid nodules was analyzed. Results: Among the 90 thyroid nodules, 43 were benign and 47 were malignant. The internal comparison of the actual malignant rate under the risk stratification level of C-TIRADS and ACR-TIRADS was statistically significant (P<0.05). The higher the classification level, the higher the malignant rate. The area under the curve of C-TIRADS and ACR-TIRADS in the diagnosis of thyroid nodules was 0.807 (95%CI 0.710 to 0.882) and 0.765 (95%CI 0.664 to 0.848), and the difference was not statistically significant (P>0.05). The sensitivity of C-TIRADS was lower than that of ACR-TIRADS (78.7% vs 93.6%), and the specificity was higher than that of ACR-TIRADS (72.1% vs 58.1%). The sensitivity of C-TIRADS combined with SWE diagnosis was 95.7%, and the specificity was 72.1%, which was higher than that of single C-TIRADS diagnosis (P<0.05). Conclusion: The efficacy of C-TIRADS in the differential diagnosis of benign and malignant thyroid nodules is close to that of ACR-TIRAD, and it has higher specificity, which helps to reduce unnecessary puncture. The combination of SWE can further improve the diagnostic efficiency and provide better guidance for clinical decision-making.

Keywords: thyroid nodules; ultrasound; C-TIRADS guide; shear wave elastography; diagnosis

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