对比不同流速丙泊酚在人工流产手术中的应用效果
作者: |
1王超,
1肖广莉
1 上海交通大学医学院附属第九人民医院麻醉科,上海 201999 |
通讯: |
肖广莉
Email: jymz20220217@163.com |
DOI: | 10.3978/j.issn.2095-6959.2022.07.020 |
摘要
Comparison of application effect of propofol with different flow rates in induced abortion
CorrespondingAuthor: XIAO Guangli Email: jymz20220217@163.com
DOI: 10.3978/j.issn.2095-6959.2022.07.020
Abstract
Objective: To compare and analyze the effects of propofol with different flow rates in induced abortion. Methods: A total of 114 outpatients of our hospital who underwent induced abortion from July 2019 to July 2021 were selected as the research subjects. They were divided into group A and group B by random number table method, with 57 cases in each group. They were injected with propofol (3.0 mg/kg) for intravenous anesthesia according to 10 s (group A) and 30 s (group B) respectively. The anesthesia conditions (including the success rate of sedation, the onset time of anesthesia, the recovery time, the time of leaving the room, the number and times of additional anesthetic drugs) of the two groups were recorded and compared. In addition, the systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and pulse oxygen saturation (SpO2) before anesthesia (T0), when the vaginal dilator was placed (T1), during uterine aspiration (T2) and 10 min after operation (T3) were compared between the two groups. The inhibition of respiratory and circulatory circulation during operation was analyzed, and the adverse reactions after operation were recorded. Results: The success rate of sedation in both groups was 100% (57/57). Compared with group A, the onset time of anesthesia in group B was significantly longer (P<0.05), and there was no significant difference in anesthesia recovery time, departure time, number of additional cases and times between the two groups (P>0.05); compared with T0, SBP and SpO2 decreased significantly at T1, T2 and T3 in the two groups (P<0.05), and gradually recovered at T3. In addition, SpO2 at T1 in group A was significantly lower than that in group B (P<0.05); the incidence of respiratory depression (intraoperative SpO2 <95%) after induction in group A was significantly higher than that in group B (P<0.05). In addition, the number of primary respiratory support given in group A was significantly higher than that in group B (P<0.05), and the proportion of patients whose SBP decreased by more than 20% during operation was significantly higher than that in group B (P<0.05); the postoperative adverse reactions included nausea, vomiting, salivation, chills, dizziness (aftereffect of anesthesia during anesthesia awakening), but the symptoms were mild and naturally relieved without treatment. There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion: Patients undergoing induced abortion are relatively slow to implement spontaneous respiratory intravenous anesthesia (more than 30s is recommended). The injection flow rate can reduce the inhibition of respiration and circulation and the fluctuation of blood pressure.