文章摘要

肠道感染与儿童生长发育的研究进展

作者: 1,2袁君茹, 3杨玮, 2李文德, 1覃冬云
1 广东医科大学药学院,广东 东莞 523808
2 广东省实验动物监测所,广州 510663
3 广东药科大学新药研发中心,广州 510006
通讯: 覃冬云 Email: 410136762@qq.com
DOI: 10.3978/j.issn.2095-6959.2022.08.036
基金: 广东省平台基地及科技基础条件建设项目(2021B1212060002)。

摘要

病原微生物引起的肠道感染是一类儿童常见临床感染性疾病,对儿童生长发育有不可忽略的消极影响。肠道病原微生物可进入宿主肠道内,破坏人体正常肠道微环境,打乱肠道内生态平衡。上述情况包括破坏肠道黏膜、增加/降低肠道通透性、抑制正常肠道微生物功能等,进而阻碍机体对营养的转化和吸收等。家长及临床工作者应提高对儿童生长环境中易出现的肠道感染微生物的防范意识。
关键词: 肠道微生物;肠道感染;儿童;生长发育

Research progress in intestinal infection and growth and development of children

Authors: 1,2YUAN Junru, 3YANG Wei, 2LI Wende, 1QIN Dongyun
1 College of Pharmacy, Guangdong Medical University, Dongguan Guangdong 523808, China
2 Guangdong Provincial Laboratory Animals Monitoring Institute, Guangzhou 510663, China
3 New Drug Research and Development Center, Guangdong Pharmaceutical University, Guangzhou 510006, China

CorrespondingAuthor: QIN Dongyun Email: 410136762@qq.com

DOI: 10.3978/j.issn.2095-6959.2022.08.036

Foundation: This work was supported by Guangdong Provincial Platform Base and Science and Technology Infrastructure Construction Project, China (2021B1212060002).

Abstract

Intestinal infection caused by pathogenic microorganisms are a common group of clinical infectious diseases in children. Recently, it has been found that enteric microorganisms have a negative impact on the growth and development of children. Enteric pathogenic microorganisms can enter the host intestine, disrupt the normal intestinal microenvironment of the human body, and disturb the ecological balance in the intestine. That includes damage to the intestinal mucosa, increase/decrease of intestinal permeability, inhibition of normal intestinal microbial function, etc., thereby hindering the transformation and absorption of nutrients by the body. Parents and clinical workers should raise awareness of the prevention of intestinal infection microorganisms that are prone to occur in children’s growing environment.

Keywords: enteric microorganisms; intestinal infections; children; growth and development

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