It has become a consensus in the field of cardio-cerebrovascular disease that atherosclerosis is an inflammatory response disease, and inflammation cells involved in atherosclerotic are varied, including mononuclear-macrophages, dendritic cells, T lymphocytes and neutrophils, etc. Neutrophil extracellular traps (NETs) are mesh structure released by activated neutrophils. They have diverse biological activities, such as anti-inflammatory and proinflammatory effect, procoagulant activity. They also participate in pathological processes of many kinds of diseases. A number of studies found that neutrophils can be activated by some stimulating factor and release NETs. NETs have cytotoxic and pro-thrombotic effects, and the ability to interact with macrophages, they play an important role in atherosclerosis pathology as a link between inflammation and thrombosis.