Objective: To explore the effect of introducing symptom management strategies in health education for patients with chronic heart failure. Methods: A total of 110 patients with chronic heart failure treated in our hospital from December 2019 to December 2020 were randomly divided into a control group and an observation group, 55 cases in each group. Three cases in each group were lost to follow-up within 6 months of intervention, and 52 cases were included in the analysis. The control group received routine health education, and the observation group was introduced symptom management strategies on this basis. The changes in heart failure symptoms, symptom management self-efficacy, heart function, and quality of life before and after the intervention were compared between the 2 groups. Results: After 6 months of the intervention, the scores of physical symptoms, psychological symptoms, and heart failure symptoms in the observation group were lower than those in the control group (P<0.05); the self-efficacy scores of symptom management in the observation group were higher than those in the control group (P<0.05); the levels of left ventricular end diastolic dimension (LVDD), left ventricular ejection fractions (LVEF), and stroke volume (SV) of the observation group were higher than those of the control group, and the BNP level was lower than that of the control group (P<0.05); the Minnesota Living with Heart Failure Questionnaire (MLHFQ) scores of the observation group were lower than those of the control group (P<0.05). Conclusion: The introduction of symptom management strategies in the health education for patients with chronic heart failure can not only relieve the clinical symptoms of patients, enhance the self-efficacy of symptom management, but also significantly improve cardiac function and quality of life.