文章摘要

孤立性肺结节的循证医学影像处理

作者: 1Yi-Xiang J. Wang, 2Jing-Shan Gong, 3Kenji Suzuki, 4Sameh K. Morcos
1 Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
2 Department of Radiology, Shenzhen People's Hospital, Jinan University Second Clinical Medicine College, Shenzhen 518020, China
3 Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
4 Diagnostic Imaging, The University of Sheffield, Sheffield, UK
通讯: Yi-Xiang J. Wang Email: yixiang_wang@cuhk.edu.hk
DOI: 10.3978/j.issn.2095-6959.2015.02.001

摘要

孤立性肺结节(solitary pulmonary nodule,SPN)定义为被肺实质包绕的直径≤3 cm的圆形/类圆形不 透明影。大多数吸烟者的薄层CT扫描均可以发现SPN,其中大部分直径<7 mm。在过去,如偶然 发现此类结节临床采用2年以上随访,包括3,6,12,18,24个月的CT随访。该方案使随访者接受 的辐射量增加。结节形态特性,如形状、边缘特征、空洞、位置等难以准确鉴别良恶性结节。当 首次检查中的SPN不能定性时,应评估包括患者年龄和吸烟史等危险因素。Fleischner学会2005年 指南指明所有4 mm或更小的结节中至少99%为良性;当结节直径为5~9 mm时,最佳策略是随访。 随访检查的时间点依据结节大小(4~6,6~8 cm)和患者病史而不一,特别是是否存在恶性肿瘤低危 /高危因素。直径>8 mm的非钙化结节高度提示恶性肿瘤,此时应考虑额外检查如造影剂增强CT, 正电子发射断层扫描(positron emission tomography,PET),经皮肺穿刺活检,胸腔镜切除术或电 视辅助胸腔镜切除术。
关键词: 肺结节 计算机断层成像 随访 正电子发射断层成像 磁共振成像 指南 活检 肺癌

Evidence-based imaging processing of solitay pulmonary nodule

Authors: 1Wang Yi-Xiang J., 2Gong Jing-Shan, 3Suzuki Kenji, 4Morcos Sameh K.
1 Department of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
2 Department of Radiology, Shenzhen People's Hospital, Jinan University Second Clinical Medicine College, Shenzhen 518020, China
3 Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
4 Diagnostic Imaging, The University of Sheffield, Sheffield, UK

CorrespondingAuthor: Wang Yi-Xiang J. Email: yixiang_wang@cuhk.edu.hk

DOI: 10.3978/j.issn.2095-6959.2015.02.001

Abstract

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