尤文肉瘤易误诊为小细胞肺癌1例临床病理分析
| 作者: |
1姜春婷,
2魏建国,
1许春伟,
1吴永芳,
1王怀涛,
1王海艳,
1张博,
1邵云,
1李晓兵
1 军事医学科学院附属医院病理科，北京 100071 2 浙江省绍兴市人民医院病理科，浙江 绍兴 312000 |
| 通讯: |
邵云
Email: shysep@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2015.06.064 |
摘要
目的：探讨尤文肉瘤的临床病理学特征，避免误诊影响治疗。方法：分析1例36岁女性肺转移性尤文肉瘤患者临床表现、组织学特征和免疫表型特点，并复习相关文献，了解该肿瘤的病因、临床表现、鉴别诊断。结果：尤文肉瘤是一种比较少见的骨肿瘤，无特异性临床表现，本例患者主要发现肺部占位，曾有过尤文肉瘤病史，临床需要在肺原发的小细胞性恶性肿瘤与转移的尤文肉瘤进一步鉴定，最后病理结果为小细胞恶性肿瘤，结合病史及免疫组织化学染色结果符合骨尤文肉瘤肺转移。结论：尤文肉瘤发生肺转移者较为少见，易误诊为小细胞肺癌，应加强对尤文肉瘤的临床及病理学特征的认识并结合病史，避免或减少误诊误治。
关键词：
肺
尤文肉瘤
小细胞肺癌
误诊
One case of clinicopathological analyses of Ewing’s sarcoma easy to misdiagnosis as small cell lung cancer
CorrespondingAuthor: SHAO Yun Email: shysep@163.com
DOI: 10.3978/j.issn.2095-6959.2015.06.064
Abstract
Objective: To explore the Ewing’s sarcoma characteristics of clinicopathology, so as to avoiding the misdiagnosis influence treatment. Methods: The clinical data, histopathologic observation and immunohistochemical staining were studied in one case of pulmonary metastatic Ewing’s sarcoma, in order to explore their etiology, clinical manifestations and differential diagnosis combined with literatures. Results: Ewing’s sarcoma is a rare bone tumor without specific clinical features. This patient was mainly found lung placeholder, with history of Ewing’s sarcoma, and clinical doctors needed tell the difference between the lungs of primary small cell malignant tumor and metastasis Ewing’s sarcoma, the final pathology results were the small cell malignant tumor, combining with the history and immunohistochemical staining results accord with bone Ewing’s sarcoma pulmonary metastasis. Conclusion: Ewing’s sarcoma pulmonary metastasis is a rare, easily misdiagnosed as small cell lung cancer, so we should strengthen the understanding of Ewing’s sarcoma clinical and pathological features with combining with the history, avoiding or reducing the errors.