燕麦β-葡聚糖降血脂作用的研究进展
| 作者: |
1于永华,
1徐飞飞,
1林琳,
1黄明莉
1 哈尔滨医科大学附属第一医院产科，哈尔滨 150001 |
| 通讯: |
黄明莉
Email: doctor_hml@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2022.02.034 |
摘要
燕麦β-葡聚糖作为可溶性膳食纤维的一种，降脂、降糖作用明显，尤其是降脂效果显著。随着冠心病(coronary heart disease，CHD)发生率的升高，寻求安全有效的降脂方法尤为重要。对燕麦β-葡聚糖的理化性质、安全性及应用进行阐述，表明燕麦β-葡聚糖对细胞无毒性，其效果与黏度密切相关，可应用于降血脂、降糖、抗氧化作用等方面。此外还分析燕麦β-葡聚糖的降脂作用及机制，研究表明燕麦β-葡聚糖通过影响胆固醇的合成、吸收、排泄等过程，从而不同程度地改善血脂指标。
关键词：
燕麦β-葡聚糖；生理作用；血脂；总胆固醇；低密度脂蛋白胆固醇
Research progress on the hypolipidemic effect of oat β-glucan
CorrespondingAuthor: HUANG Mingli Email: doctor_hml@163.com
DOI: 10.3978/j.issn.2095-6959.2022.02.034
Abstract
Oat β-glucan, as a kind of soluble dietary fiber, has obvious lipid-lowering and glucose-lowering effect, especially its lipid-lowering effect. With the increasing incidence of coronary heart disease (CHD), it is particularly important to find a safe and effective method to lower lipid. The physical and chemical properties, safety and application of oat β-glucan were described. The results showed that oat β-glucan was non-toxic to cells, and its effect was closely related to viscosity, and could be used in reducing blood lipids, reducing blood sugar, antioxidation and so on. In addition, the lipid-lowering effect and mechanism of oat β-glucan were analyzed. The results showed that oat β-glucan could improve the blood lipid index in varying degrees by affecting the synthesis, absorption and excretion of cholesterol.
Keywords：
oat β-glucan; physiological role; blood lipids; total cholesterol; low density lipoprotein cholesterol