Objective: To investigate the effect of cardiac rehabilitation intervention on cardiac function in patients with H-type hypertension complicated with heart failure with preserved ejection fraction (HFPEF). Methods: All 55 patients with H-type hypertension and HFPEF in the Department of Cardiology of the First Hospital of Qinhuangdao City from January 2015 to January 2017 were enrolled as the control group, and they were given routine drug treatment and nursing. 60 patients with H-type hypertension and HFPEF admitted from February 2017 to February 2019 were enrolled as the observation group, and they were given cardiac rehabilitation intervention on the basis of the control group. The changes of blood pressure and cardiac function before and after intervention were compared between the 2 groups. Results: The systolic blood pressure, diastolic blood pressure and Hcy in the observation group were lower than those in the control group 3 months after intervention, and the difference was statistically significant (P<0.05). After 3 months of intervention, the left atrial volume/body surface area (LAVI) of the observation group was smaller than that of the control group; the 6-minute walking distance was longer than that of the control group, and the ratio of mitral E/A peak velocity (E/A) was larger than that of the control group and the difference was statistically significant (P<0.05). Conclusion: Cardiac rehabilitation intervention can reduce blood pressure level, improve left atrial pump function and exercise endurance in patients with H-type hypertension and HFPEF.