胰腺癌中的静脉血栓形成机制
| 作者: |
1李月月,
1史家岚
1 哈尔滨医科大学附属第一医院血液科，哈尔滨 150001 |
| 通讯: |
史家岚
Email: shi157655@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2021.10.030 |
摘要
胰腺癌(pancreatic cancer，PC)是一种高转移性的恶性肿瘤，其发生静脉血栓栓塞(venous thromboembolism，VTE)的风险明显高于其他肿瘤。目前，PC患者发生VTE的机制仍不清楚，可能涉及凝血系统激活、肿瘤细胞相关炎症因子产生增多等，因此仍需对PC患者VTE的发生机制作更进一步的研究。
关键词：
胰腺癌；静脉血栓栓塞；炎症因子；凝血功能异常
Mechanisms of venous thrombosis in pancreatic cancer
CorrespondingAuthor: SHI Jialan Email: shi157655@163.com
DOI: 10.3978/j.issn.2095-6959.2021.10.030
Abstract
Pancreatic cancer (PC) is a highly metastatic malignant tumor, and its risk of developing venous thromboembolism (VTE) is significantly higher than that in other tumors. Currently, the mechanism of VTE in PC patients remain unclear, which may involve the activation of blood coagulation system and increased production of tumor cell- associated inflammatory cytokines and so on. Therefore, further studies to investigate the pathogenesis of VTE in PC patients are still warranted.
Keywords：
pancreatic cancer; venous thromboembolism; inflammatory cytokines; coagulant dysfunction