1 昆明医科大学第一附属医院血液内科，昆明 650032
Pharmacokinetics and individualized prevention and treatment of hemophilia
CorrespondingAuthor: LI Chengping Email: email@example.com
Foundation: This work was supported by Joint Project of Applied Basic Research in Yunnan Province, China (2017NS047).
Hemophilia is a hemorrhagic disease caused by a genetic mutation that leads to a deficiency of coagulation factors. Due to the continuous development of hemophilia management concept, the preferred treatment now is preventive treatment. There are significant differences in the pharmacokinetics of coagulation factors in different patients and the types of bleeding in different patients, and doctors can tailor the treatment according to the pharmacokinetic data of patients to minimize the inconvenience and discomfort of the patients and avoid high treatment costs as far as possible. Therefore, individualized prevention is important and may lead to more accurate doses of preventive treatment, which is conducive to precision treatment.Keywords： hemophilia; pharmacokinetics; individualized prevention and treatment