显微镜下多血管炎肺损害发病机制及治疗进展
| 作者: |
1朱轩池,
2刘秀梅
1 山西医科大学第一临床医学院，太原 030001 2 山西医科大学第一医院风湿免疫科，太原 030001 |
| 通讯: |
刘秀梅
Email: fsklxm@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2021.05.030 |
摘要
显微镜下多血管炎(microscopic polyangiitis，MPA)是一种以累及小血管为主的系统性血管炎，可造成全身多个重要组织、脏器的损害。肺是其常见的受累器官，主要可表现为肺间质纤维化、弥漫性肺泡出血(diffuse alveolar hemorrhage，DAH)等。近年来随着对MPA肺损害发病机制认识的不断深入，对MPA肺受累的治疗也取得了新的进展。
关键词：
显微镜下多血管炎；肺间质纤维化；弥漫性肺泡出血；发病机制；治疗方案
Research progress in pathogenesis and treatment of pulmonary injury in microscopic polyangiitis
CorrespondingAuthor: LIU Xiumei Email: fsklxm@163.com
DOI: 10.3978/j.issn.2095-6959.2021.05.030
Abstract
Microscopic polyangiitis (MPA) is a kind of systemic vasculitis which mainly involves small blood vessels and can cause damage to multiple important issues and organs throughout the body. The lung is a common affected organ, which mainly manifests as pulmonary interstitial fibrosis, diffuse alveolar hemorrhage and so on. In recent years, with the in-depth understanding of the pathogenesis of pulmonary injury in MPA, new progress has been made in the treatment of lung involvement in MPA.
Keywords：
microscopic polyangiitis; pulmonary interstitial fibrosis; diffuse alveolar hemorrhage; pathogenesis; therapeutic schemes