Objective: To investigate the effect of limited fluid resuscitation (LFR) combined with multimodal pain management on the recovery, pressure sore incidence and visual analogue scale (VAS) of patients with traumatic hemorrhagic shock (THS) in lower extremity fractures. Methods: Sixty patients with lower extremity fracture and THS were randomly divided into a control group and a study group with 30 cases in each. Patients in both groups were treated with early full conventional fluid resuscitation. Patients in the control group were given traditional analgesic measures at the same time, while patients in the study group were given multi-mode pain management. The treatment, pain score, recovery and the incidence of pressure sore were compared between the 2 groups. Results: 1) Comparison of rescue: there was no significant difference between the study group and the control group in rescue success rate, mortality rate, ARDS, MODS incidence rate (P>0.05); there was no significant difference between the study group and the control group in resuscitation time, infusion volume, blood transfusion volume (P>0.05). After resuscitation, the ISS of the two groups was significantly lower than before treatment, and there was no significant difference between the 2 groups after the treatment (P>0.05). There was no significant difference in HCT, PCT, PLLA and Pt between the control group and the study group (P>0.05); the inflammatory mediators TNF-α, IL-10 and IL-6 in the study group were significantly lower than those in the control group (P>0.05). 2) Recovery comparison: the start time and fracture healing time of functional exercise in the study group were significantly shorter than those in the control group, and the compliance of functional exercise in the study group was significantly better than that in the control group (86.67% vs 63.33%, χ2=4.356, P<0.05). 3) VAS score comparison: the VAS scores of the study group were significantly lower than that of the control group (P<0.05). 4) Comparison of the incidence and satisfaction of pressure sore: the incidence of pressure sore in the study group was significantly lower than that in the control group, and the evaluation of pain management during hospitalization and the satisfaction score of medical staff were significantly higher than those in the control group (P<0.05). Conclusion: The effect of limited fluid resuscitation on patients with lower extremity fracture and traumatic hemorrhagic shock is significant. It can improve the shock state of patients rapidly and effectively. On this basis, combined with multi-mode analgesia management can effectively reduce pain relief, help patients to exercise early after operation, promote fracture healing, effectively reduce the occurrence of pressure sore complications and improve the patients’ satisfaction with medical staff is worthy of clinical application.