文章摘要

外周血嗜酸性粒细胞在哮喘和慢性阻塞性肺疾病中的研究进展

作者: 1李希, 1张家春, 1骆书刚, 1邓勇, 1党傲, 1马丽娟, 1冯静, 2胡瑞成
1 成都市第六人民医院内四科,成都 610081
2 湖南省人民医院呼吸内科,长沙 410016
通讯: 胡瑞成 Email: huruicheng@hotmail.com
DOI: 10.3978/j.issn.2095-6959.2020.06.037

摘要

外周血嗜酸性粒细胞作为一个简便易得、入院必备检查项目,可帮助评估哮喘和慢性阻塞性肺疾病患者的病情及判断其预后。嗜酸性粒细胞在过敏性疾病和寄生虫感染中发挥重要作用,但在人体免疫反应中的详尽机制尚未被充分研究。关于嗜酸性粒细胞在慢性呼吸系统疾病,尤其是在哮喘和慢性阻塞性肺疾病中的作用其关注度越来越高。
关键词: 嗜酸性粒细胞;支气管哮喘;慢性阻塞性肺疾病

Research progress of eosinophils in chronic obstructive pulmonary disease and bronchial asthma

Authors: 1LI Xi, 1ZHANG Jiachun, 1LUO Shugang, 1DENG Yong, 1DANG Ao, 1MA Lijuan, 1FENG Jing, 2HU Ruicheng
1 Department of Respiratory Medicine, Six People’s Hospital of Chengdu, Chengdu 610081, China
2 Department of Respiratory Medicine, People's Hospital of Hunan Province, Changsha 410016, China

CorrespondingAuthor: HU Ruicheng Email: huruicheng@hotmail.com

DOI: 10.3978/j.issn.2095-6959.2020.06.037

Abstract

Peripheral blood eosinophils, as a simple, accessible and necessary examination item in hospital, which can help to assess the condition and prognosis of patients with asthma and chronic obstructive pulmonary disease (COPD). Eosinophils play an important role in allergic diseases and parasitic infections, but the detailed mechanism has not been fully studied in human immune response. More and more attention has been paid to the role of eosinophils in chronic respiratory diseases, especially in asthma and COPD. This review focuses on the clinical evidence of eosinophils in asthma and COPD.
Keywords: eosinophil; bronchial asthma; chronic obstructive pulmonary disease

文章选项