1例菊池病并文献复习
| 作者: |
1赵立聪,
2贾建伟,
2赵洁
1 天津中医药大学研究生院，天津 301617 2 天津市第二人民医院中西医结合I科，天津 300192 |
| 通讯: |
赵洁
Email: jennifer.zhao@126.com |
| DOI: | 10.3978/j.issn.2095-6959.2020.05.044 |
| 基金: | 国家重大科技专项“十二五”课题(2012ZX10004301004)。 |
摘要
菊池病以发热、淋巴结肿大和白细胞减少为主要症状。菊池病的临床表现与实验室检查结果无特异性，疾病的诊断依据淋巴结病理活检及免疫组织化学结果。本例患者表现为稽留热、白细胞减少及多部位浅表淋巴结肿大，并且初始疑为布鲁氏菌病。该患者经淋巴结活检及免疫组织化学检查后确诊为组织细胞坏死性淋巴结炎，激素治疗有效，体温恢复正常，淋巴结减小，白细胞恢复至正常。
关键词：
菊池病；病例报告；诊断
Kikuchi disease: A case report and literature review
CorrespondingAuthor: ZHAO Jie Email: jennifer.zhao@126.com
DOI: 10.3978/j.issn.2095-6959.2020.05.044
Foundation: This work was supported by the 12th Five Year Plan of National Science and Technology Major Project, China (2012ZX10004301004).
Abstract
Kikuchi disease was first reported in Japan in 1972, with fever, lymphadenopathy, and leukopenia as the main symptoms. The clinical manifestations and laboratory results of Kikuchi disease have no specific indicators. The diagnosis of the disease requires lymph node biopsy and immunohistochemistry to confirm the diagnosis. This paper reports a case of brucellosis initially suspected of manifesting as missed fever, leukopenia and multiple superficial lymph node enlargement. After lymph node biopsy and immunohistochemical examination, it was diagnosed as histological necrotic lymphadenitis, hormone therapy was effective, body temperature returned to normal, lymph nodes decreased, and white blood cells returned to normal.
Keywords：
Kikuchi disease; case report; diagnosis