Objective: To study the emergency nursing interventions and effects of acute myocardial infarction and cardiogenic shock. Methods: A total of 84 patients with acute myocardial infarction and cardiogenic shock who were treated in Hai’an People’s Hospital from October 2016 to October 2019 were selected. The patients in this group were divided into a control group (routine care) and a research group (emergency nursing intervention). The nursing effect of patients in the two groups was compared. Results: After the nursing intervention, the improvement of diastolic and systolic blood pressure in the study group was significantly better than that in the control group (P<0.05). The incidence of complications (9.52%) and nursing satisfaction (97.62%) were significantly higher in the study group. In the control group (23.81%) and (85.71%), the difference was statistically significant (P<0.05). Conclusion: Emergency nursing intervention for patients with acute myocardial infarction and cardiogenic shock has significant effects, can improve the success rate of patients and satisfaction with emergency care, and is worth promoting and applying.