Objective: To analyze the value of continuity nursing care mode on family management in the treatment of asthma in children. Methods: All of 80 children patients with asthma were collected who admitted to paediatrics outpatient in our hospital from January to December 2017, and divided into observation group (n=40) and control group (n=40). Observation group were given continuity nursing care mode on family management while control group were given general nursing. After 6 months intervention, the level of family management measure, pediatric asthma quality of life, therapeutic effect of asthma, et al were analysis and comparison. Results: In this study, the level of family management measure, pediatric asthma quality of life questionnaire (PAQLA) score and asthma control were significantly higher in observation group than control group; what’s more, the level of reduction fractional nitric oxide concentration in exhaled breath (FeNO) were better in observation group than control group. Conclusion: Continuity nursing care mode centered on family management improved the level of family management, symptoms and quality of life of children.