阻塞性睡眠呼吸暂停低通气综合征与抑郁情绪的相关性
| 作者: |
1陈效荣,
1裴翀,
1李秀
1 合肥市第一人民医院呼吸内科，安徽医科大学第三附属医院，合肥 230061 |
| 通讯: |
李秀
Email: pchl331@126.com |
| DOI: | 10.3978/j.issn.2095-6959.2019.06.015 |
| 基金: | 合肥市 2015 年科技攻关计划项目 ( 合科 2015-153 号 )。 |
摘要
目的：探讨阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome，OSAHS)与抑郁情绪的相关性。方法：对80例OSAHS患者和28例同期健康体检者进行睡眠监测和贝克抑郁量表(Beck Depression Inventor y，BDI)、嗜睡量表(Epwor th Sleeping Scale，ESS)问卷调查。 结果：OSAHS组较健康对照组在年龄、受教育年限、病程长短、吸烟、饮酒等方面差异无统计学意义(均P>0.05)，在BMI、呼吸暂停指数(apnea hypopnea index，AHI)、氧减指数、平均血氧饱和度(average saturation，SaO2)、最低SaO2、最长呼吸暂停时间上差异有统计学意义(均P<0.05)；OSAHS组在ESS量表和BDI抑郁量表测试中差异均有统计学意义(均P<0.05)；此外OSAHS组抑郁的发生率为38.75%，显著高于对照组的28.57%；同时抑郁与BMI呈正相关(r=0.225，P=0.031)。 结论：OSAHS能增加抑郁发生率，且OSAHS越严重，越容易发生抑郁；BMI可能是抑郁症的影响因素。
关键词：
阻塞性睡眠呼吸暂停低通气综合征；抑郁；睡眠监测
Obstructive sleep apnea hypopnea syndrome and depression
CorrespondingAuthor: LI Xiu Email: pchl331@126.com
DOI: 10.3978/j.issn.2095-6959.2019.06.015
Foundation: This work was supported by Anhui Science and Technology Project Foundation, China (No. 2015-153).
Abstract
Objective: To Explore the relationship between obstructive Sleep apnea hypopnea syndrome (OSAHS) and depression. Methods: Physical examination, Beck Depression Inventory (BDI), Epworth Sleepiness Scale (ESS) and a polysomnography test were performed in 80 patients with OSAHS and 28 healthy controls. Results: There was statistically insignificant in age, education years, course, smoking, drinking between control group and OSAHS group (P>0.05), but body mass index (BMI), apnea hypopnea index (AHI), desaturation dip rate, minimum saturation, average saturation, the longest time of apnea of OSAHS was significantly (P<0.05), there were significant differences in ESS, BDI (P<0.05); in addition, incidence of depression was 38.75% in OSAHS group, and significantly higher than those in the control group (28.57%). In the same time, there was a correlation between depression and BMI. Conclusion: OSAHS can increases the depression rate, the incidence of depression significantly higher when OSAHS is more server, BMI may be a factor in depression.
Keywords：
obstructive sleep apnea hypopnea syndrome; depression; sleep monitoring