中国汉族人群血浆三酰甘油浓度与高血压相关：一项大样本横断面研究
| 作者: |
1黄颖,
2蔡东平,
3贺永明
1 苏州大学医学部2015级临床医学卓越班，江苏 苏州 215008 2 苏州高新区狮山街道社区卫生服务中心，江苏 苏州 215011 3 苏州大学附属第一医院心内科，江苏 苏州 215008 |
| 通讯: |
贺永明
Email: heyongming@catletscore.com |
| DOI: | 10.3978/j.issn.2095-6959.2019.05.025 |
| 基金: | 国家自然科学基金 (8142918)。 |
摘要
目的：探究中国汉族人群血浆三酰甘油(tr iglycer ide，TG)浓度与高血压的相关性。方法：对 3 100例高血压病患者和2 652例非高血压病患者进行横断面研究，以确定TG与高血压病的关系。结果：TG作为连续变量时，每升高1 mmol/L，高血压病OR为 1.113， 95%CI 1.039~1.193。TG作为分类变量时，以Q1作参考分位，随着TG水平的增加，高血压病OR逐步增加(Q2：1.128，95%CI 0.914~1.392；Q3：1.249，95%CI 1.009~1.545；Q4：1.553，95%CI 1.242~1.941；Q5：1.745，95%CI 1.362~2.236)。建议诊断高血压病与非高血压病的TG的切割值为1.17 mmol/L。结论：中国汉族人群的血浆TG水平与高血压病的发生相关，且TG水平越高与高血压病的相关性越强。
关键词：
三酰甘油；高血压病；优势比；汉族人群
Triglyceride associated with primary hypertension in Chinese Han ethnic population: A cross-sectional study
CorrespondingAuthor: HE Yongming Email: heyongming@catletscore.com
DOI: 10.3978/j.issn.2095-6959.2019.05.025
Foundation: This work was supported by the National Natural Science Foundation of China (8142918).
Abstract
Objective: To explore the correlation between triglyceride and hypertension in Chinese Han population. Methods: Cross-sectional study of 3 100 cases and 2 652 controls was performed for identifying the association of TG with hypertension. Results: On a continuous scale, the risk ratios for primary hypertension per 1 mmol/L higher TG concentrations were 1.113, 95%CI 1.039–1.193. On a categorical scale, the odds ratios for hypertension were consistently and significantly stepwise increased with the increased TG quintiles (Q2: 1.128, 95%CI 0.914–1.392; Q3: 1.249, 95%CI 1.009–1.545; Q4: 1.553, 95%CI 1.242–1.941; Q5: 1.745, 95%CI 1.362–2.236). The suggested TG cutoff for discriminating hypertension from non-hypertension was 1.17 mmol/L. Conclusion: The TG level is associated with primary hypertension.
Keywords：
triglyceride; hypertension; odd ratio; Chinese Han ethnic population