摄盐量对2 型糖尿病患者三酰甘油的影响
| 作者: |
1秦文,
1匡洪宇,
1左姣,
1刘念娇,
1朱文博,
1梁苡菲,
1高昕媛
1 哈尔滨医科大学附属第一医院内分泌科，哈尔滨 150001 |
| 通讯: |
匡洪宇
Email: ydyneifenmier@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2019.04.020 |
| 基金: | 白求恩仁会糖尿病基金项目。 |
摘要
目的：探讨2型糖尿病患者摄盐量与三酰甘油的关系。方法：选取2018年1至7月在哈尔滨医科大学附属第一医院住院的2型糖尿病患者，排除合并高血压、正在服用降脂药物、肾小球滤过率(eGFR)<60 mL/min等可能影响研究结果的因素后，共选取597例。收集患者基本资料和住院期间的相关检验及检查。根据患者24 h尿钠排泄水平估算日摄盐量。应用多因素log i st ic回归分析研究2型糖尿病患者摄盐量与高三酰甘油血症的关系。结果：在调整舒张压、体重指数(BMI)、年龄、血尿酸、总胆固醇等因素后，摄盐量的增加为高三酰甘油血症的独立危险因素(P<0.05)。结论：高盐摄入会增加2型糖尿病患者发生高三酰甘油血症的风险。
关键词：
2型糖尿病；三酰甘油；摄盐量
Effect of salt intake on triglyceride in patients with type 2 diabetes
CorrespondingAuthor: KUANG Hongyu Email: ydyneifenmier@163.com
DOI: 10.3978/j.issn.2095-6959.2019.04.020
Foundation: This work was supported by the Bethune Ren Hui Diabetes Project Foundation, China.
Abstract
Objective: To explore the relationship between salt intake and triglyceride level in patients with type 2 diabetes. Methods: Excluding hypertension, taking lipid-lowering drugs, glomerular filtration rate <60 mL/min and other factors that may affect the results of the study, we classified 597 patients with type 2 diabetes, who were inpatients at the First Affiliated Hospital of Harbin Medical University in China from January 2018 to July 2018. Salt intake was estimated by 24-hour urine sample using the equation. The association between salt intake and triglyceride level were determined by logistic regression analysis. Results: After adjusting for diastolic blood pressure, BMI, age, blood uric acid, total cholesterol and other factors, high salt intake is the risk factor of hypertriglyceridemia in patients with type 2 diabetes (P<0.05). Conclusion: High salt intake may increase the risk of hypertriglyceridemia in patients with type 2 diabetes.
Keywords：
type 2 diabetes; triglyceride; salt intake