Objective: To examine the difference of clinical outcomes between advanced maternal age women aged 35–39, 40–44 and 45 and older. Methods: We collected 3 395 pregnant and parturien women from January 1, 2017 to December 31, 2017 aged ≥35 in Shengjing Hospital, and the clinical data were retrospectively analyzed. We divided the cases into three groups: 35–39 years of age groups (group 1, n=2 888), 40–44 years of age groups (group 2, n=478) and the age of 45 or higher group (group 3, n=29), and compared the three groups of clinical outcomes. Results: The incidence rates of gestational hypertension disease, pregnancy with uterine fibroids, placenta previa, postpartum hemorrhage, fetal malformation, odinopoeia and abortion rate were higher in group 2 and group 3 than those in group 1. The difference between the three groups was statistically significant (P<0.05). With the increase of age, the average birth weight and the average gestational week of childbirth showed a decreasing trend, and the difference was statistically significant (P<0.05). The incidence of premature birth was higher in the group 3 than in the other two groups, and the difference was statistically significant (P<0.05). Conclusion: The clinical outcome was worse in advanced maternal age women over 40 years old. Monitoring during pregnancy should be strengthened to better ensure the health and safety of the mother and child.