To explore the clinicopathologic features, immunophenotype, differential diagnosis, treatment, and prognosis of villoglandular adenocarcinoma (VGA) of the uterine cervix, the clinicopathological features and immunophenotypes of 9 cases of VGA were analyzed by light microscopy and immunohistochemistry, and the related literatures were reviewed. Nine cases of VGA were 39–62 years old, with an average age of 50.8 years. The clinical manifestations were irregular vaginal bleeding or abnormal menstruation. Under colposcopy, 6 cases were cervical exogenic masses and 3 cases were cervical erosion. HPV was mostly positive. Microscopically, we can see abundant of long and thin villoglandular architectures, most papillary architectures contain the central fibrovascular axis, which consists of stroma cells and many inflammatory cells. Tumor cells represent a shape of low column and a round nuclear, with mild to moderate nuclear atypia, of which 7 cases infiltrate less than 1/3 fibromuscular layer. Of the 9 cases of VGA, only one case caused an invasion of endometrium, and the remaining 8 cases did not invaded the nerve, vessel or surrounding organs. Immunophenotype: CEA, p16 were positive in tumor cells, while Vimentin was negative. ER and PR depended on the individuals. Ki-67 LI was 30%–90%. VGA is a rare adenocarcinoma of the uterine cervix, which is difficult to differentiate it from other cervical adenocarcinoma by clinical manifestations. The diagnosis should be based on its histopathological features and immunohistochemical staining. VGA usually has a favorable prognosis, so it matters to take carefully to avoid the excess of the therapy.