不同时间服用盐酸达克罗宁胶浆对胃镜检查效果的影响
| 作者: |
1,2王师军,
1,2,3田旭,
1,2陈伟庆,
1,2刘邦伦
1 肿瘤转移与个体化诊治转化研究重庆市重点实验室，重庆大学附属肿瘤医院/重庆市肿瘤研究所/重庆市肿瘤医院， 重庆 400030 2 教育部生物流变科学与技术重点实验室(重庆大学)，重庆大学附属肿瘤医院/重庆市肿瘤研究所/ 重庆市肿瘤医院，重庆 400044 3 《TMR整合护理学杂志》编辑部，天津 300020 |
| 通讯: |
刘邦伦
Email: cqch_liubl@163.com |
| DOI: | 10.3978/j.issn.2095-6959.2019.01.009 |
| 基金: | 重庆大学附属肿瘤医院/ 重庆市肿瘤医院临床研究基金(LY2017004)。 |
摘要
目的：探讨不同时间服用盐酸达克罗宁胶浆对胃镜检查效果的影响。方法：2018年5月至8月， 426例门诊胃镜检查患者，采用电脑随机化数字表等比例分为检查前5 min组(A组)、检查前10 min 组(B组)和检查前15 min组(C组)，比较分析各组插镜及麻醉效果、祛泡效果及安全性。结果：共420例患者完成检查，且检查中均未出现良反应。B组插镜及麻醉效果优于C组，差异有统计学意义(χ2=13.52，P=0.004)。B组祛泡效果优于A组(χ2=9.83，P=0.02)与C组(χ2=13.47，P=0.004)，差异有统计学意义。结论：胃镜检查前10 min口服盐酸达克罗宁可提高插镜及麻醉效果和祛泡效果。
关键词：
胃镜检查；盐酸达克罗宁胶浆；咽喉局部麻醉；祛泡效果
Effect of different administration time of orally dyclonine hydrochloride mucilage on gastroscopy results
CorrespondingAuthor: LIU Banglun Email: cqch_liubl@163.com
DOI: 10.3978/j.issn.2095-6959.2019.01.009
Foundation: This work was supported by the Clinical Research Foundation of Chongqing University Cancer Hospital & Chongqing Cancer Hospital, China (LY2017004).
Abstract
Objective: To explore the impact of opportunity of taking orally dyclonine hydrochloride mucilage on the performance of gastroscopy. Methods: A total of 426 patients who presented between May and August 2018 were randomly assigned into groups A, B, and C. Groups A, B, and C were instructed to taking orally dyclonine hydrochloride mucilage at 5, 10, and 15 min before gastroscopy, respectively. After completed all colonoscopies, the effect of gastroscopy insertion and anesthesia, antifoam effect and adverse events were evaluated. Results: A total of 420 outpatients completed the examination, and no adverse events were detected in the whole examination. Finally, we found that the effect of gastroscopy insertion and anesthesia in group B was superior to that of group C (χ2=13.52, P=0.004), and antifoam effect in group B was also better than that of group A (χ2=9.83, P=0.02) and C (χ2=13.47, P=0.004). Conclusion: It is promising option to instruct patients undergoing gastroscopy taking orally dyclonine hydrochloride mucilage at 10 min before gastroscopy because this approach can improve the effect of gastroscopy insertion and anesthesia and antifoam effect.
Keywords：
gastroscopy; dyclonine hydrochloride mucilage; topical pharyngeal anesthesia; antifoam effect