Objective: To discuss psychological and physical influence and patient satisfaction of psychological nursing to elderly preoperative patients. Methods: A total of 102 elderly preoperative patients were randomly divided into observation group and control group. Patients in control group accept traditional nursing and observation group accept psychological nursing based on traditional nursing, whose heart rate, blood pressure, Symptom Check List-90 (SCL-90) score, nursing care satisfaction were compared and analyzed. Results: The heart rate and blood pressure of the two groups in second day had no statistical significance (P>0.05), but after corresponding nursing, on operation day and the next day of operation, the heart rate and blood pressure of observation group were significantly lower than that of control group (P<0.05). The SCL-90 score of two groups were not significant on the second day (P>0.05), while on operation day and the next day of operation, somatization, anxiety, fear scores in SCL-90 scale of the psychological care group were significantly lower than those of the control group (P<0.05); and the nursing care satisfaction was significantly higher than that of the control group (P<0.05). Conclusion: Psychological nursing on the basis of routine nursing of elderly preoperative patients can effectively control their heart rate and blood pressure, also can improve the psychological status and the nursing satisfaction of these elderly patients.