Objective: To investigate the diagnostic value of dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) time signal curve (TIC) and related quantitative parameters in sinonasal neoplasms. Methods: A total of 180 patients with nasal sinus in Xiangya Hospital Central South University from February 2015 to February 2017 were enrolled, all patients were pathologically diagnosed. The patients obtained preoperative DCE-MRI scanning, gained TIC and related quantitative parameters, with surgical pathology diagnosis as the gold standard, the effect of the TIC of DCE-MRI and the related quantitative parameters of diagnosis were analyzed. Receiver-operating characteristic (ROC) curve was used to analyze the sensitivity and specificity of each parameter’s prediction on nasal cavity and sinus tumors; the Kappa test was used to analyze the consistency of DCE-MRI and the pathological diagnosis. Results: Ninety-six cases (53.33%) of benign tumors were detected by DCE MRI, and 84 cases (46.67%) of malignant, including 79.17% of patients with benign TIC curve I class, higher than that in patients with malignant, and III class accounted for 0.00%, lower than that in patients with malignant, the difference was statistically significant (P<0.05). The average tumor diameter of benign patients was (2.39±0.64) cm, which was significantly smaller than that of malignant patients (3.98±1.06) cm, and the difference was statistically significant (P<0.05). Among benign patients, rate constant (Kep), volume transfer constant (Ktrans) and extravascular extracellular volume fraction (Ve) were respectively (0.339±0.123) min⁻¹, (0.060±0.034) min⁻¹, 0.531±0.136, among which Kep and Ktrans were lower than those of malignant patients, and Ve significantly higher than malignant patients (P<0.05). By ROC curve, Kep predicted that the optimal truncation value of malignant nasal sinus tumors was 0.509 min⁻¹, with a sensitivity of 81.3% and 89.6% specificity. The best truncation value predicted by Ktrans was 0.205 min⁻¹, with a sensitivity of 84.4% and a specificity of 89.6%. The best truncation value of Ve was 0.385, sensitivity was 71.9%, and the specificity was 82.2%. The sensitivity, specificity, positive predictive value and negative predictive value of DCE-MRI diagnosis of malignant nasal sinus tumors were 88.37%, 91.49%, 90.00%, 90.48%, 89.58%, and the pathological diagnosis consistency Kappa=0.799. Conclusion: The TIC curve and quantitative parameters of DCE-MRI can provide more information for the identification of nasal sinus tumor, and it is well diagnosed and worthy of clinical promotion.