A 58-year-old male patient was admitted to 371 Central Hospital of the PLA for “the abdominal mass 3 days ago”. The patient had a liver transplant in our hospital because of the primary liver cancer 10 years ago. PET-CT scan showed a leaf shaped soft tissue mass on the left mesenteric mesentery, which was considered to be a primary mesenteric tumor or a hepatic metastatic carcinoma. There was no occupying lesion in the liver. Postoperative pathological diagnosis showed the middle differentiated adenocarcinoma, which might be caused by the metastasis of primary liver cancer. Mesenteric metastatic carcinoma was a kind of hepatocellular carcinoma, which was relatively rare. The reason might be that the vena cava was off and the postoperative immunization avoidance. So postoperative follow-up should be performed closely, which could lead to a longer life for the patients.