罕见部位脂肪肉瘤的诊断及文献复习
| 作者: |
1周冬梅,
1陈丽芳,
1张红,
1朱伟峰,
1何银珠,
1许春伟
1 福建省肿瘤医院，福建省医科大学附属肿瘤医院病理科，福建省肿瘤医学转化重点实验室，福州 350014 |
| 通讯: |
周冬梅
Email: fjzdm.2004@126.com |
| DOI: | 10.3978/j.issn.2095-6959.2017.11.014 |
摘要
目的: 分析6例罕见部位脂肪肉瘤的临床病理特征以提高诊断认识。方法: 常规HE染色分析肿 瘤形态，免疫组织化学方法分析肿瘤细胞分化方向。结果: 6例均可见多少不等脂肪母细胞及不 同分化程度的脂肪细胞，部分黏液变或纤维硬化。免疫组织化学周期依赖性蛋白激酶4(cyclin- dependent kinases，CDK4)，MDM2及S-100阳性。结论: 罕见部位的脂肪肉瘤结合病史、形态及组 织化学等并不难诊断，关键在于不要受常规诊断思路局限，才能避免误诊。
关键词：
脂肪肉瘤
罕见
病理
诊断
Diagnosis of liposarcoma in rare part and literature review
CorrespondingAuthor: Zhou Dongmei Email: fjzdm.2004@126.com
DOI: 10.3978/j.issn.2095-6959.2017.11.014
Abstract
Objective: To improve diagnosis by the analysis of the clinicopathologic characteristics of 6 liposarcoma cases. Methods: e morphology of tumor was analyzed by routine HE staining, and the di erentiation of tumor cells was analyzed by immunohistochemical method. Results: We saw some lipoblasts and di erential lypocytes in the 6 cases, some of which showed mucoid degeneration and brosis. Cyclin-dependent kinases (CDK4), MDM2 and S-100 were positive in tumor cells. Conclusion: It is not di cult to diagnosis liposarcoma in rare site, combined with history, morphology and histochemistry, etc. It is crucial that we should not be limited by conventional diagnostic thinking and then misdiagnosis can be avoided.
Keywords：
liposarcoma
rare
pathology
diagnosis