男性肺原发性绒毛膜癌1例并文献复习
作者: |
1浦学慧,
2李海,
3丁宁,
1陈爱萍
1 南京医科大学第一附属医院放射科,南京 210029 2 南京医科大学第一附属医院病理科,南京 210029 3 南京医科大学第一附属医院呼吸与危重症医学科,南京 210029 |
通讯: |
陈爱萍
Email: chenaiping-123@163.com |
DOI: | 10.3978/j.issn.2095-6959.2017.08.035 |
基金: | 江苏高校优势学科建设工程资助项目, JX10231801 |
摘要
回顾性分析南京医科大学第一附属医院通过手术切除病理确诊的1例男性肺原发性绒毛膜癌(primary choriocarcinoma,PCC)的临床资料、影像学及组织病理学等特征,结合国内外文献复习,总结肺PCC的诊断及治疗进展。男性肺PCC是一种较为罕见高度恶性生殖细胞肿瘤,病因不明,临床表现多样,咯血最常见。早期诊断困难,易误诊为常见病,预后差,致死率高。手术联合化疗是目前较为提倡的治疗方案。男性肺PCC的诊断较难,需结合临床、影像学等综合分析,确诊需依赖组织病理学。
关键词:
原发性绒毛膜癌
肺
人绒毛膜促性腺激素
Primary pulmonary choriocarcinoma in a male: a case report and literature review
CorrespondingAuthor: CHEN Aiping Email: chenaiping-123@163.com
DOI: 10.3978/j.issn.2095-6959.2017.08.035
Abstract
The report retrospectively analyzed the clinical data, imaging and histopathological characteristics of one case of male with pulmonary primary choriocarcinoma (PCC) confirmed by pathological diagnosis, reviewed other cases from the related literature, and summarized the diagnosis and treatment progress. The male primary choriocarcinoma was a rare malignant germ cell tumors with unknown etiology and diverse clinical manifestations, among which hemoptysis was the most common symptom. Early diagnosis of this cancer was difficult, and it was often misdiagnosed as common diseases, with poor prognosis and high fatality rate. The advocate treatment for this disease was operation in combination with chemotherapy. The diagnosis of primary pulmonary choriocarcinoma was difficult, which should be combined with clinical and radiographic analysis, and final diagnosis still depended on histopathology.
Keywords:
primary choriocarcinoma
Lung
human chorionic gonadotrophin