Objective: To investigate the effects of early rehabilitation nursing on complications and the living ability in hypertensive patients with intra-cerebral evacuation of hematoma. Methods: A total of 120 hypertensive patients with intra-cerebral evacuation of hematoma were included in the study, in which the control group of 60 patients was given with routine care, while the observation group of 60 patients was given early rehabilitation nursing, and the nursing effects of two groups were compared. Results: After nursing intervention, the MBI, ESS and GCS scores had been significantly improved compared with the control group, and the incidence of postoperative complications in patients of the observation group was significantly lower than that of the control group. Conclusion: Early rehabilitation nursing interventions for hypertensive patients with intra-cerebral hematoma is of great significance, which can effectively improve the patient’s neurological function, promote patient’s activities, thereby improving the quality of life of patients.