Asthma is a chronic inflammatory airway disease, and its pathological process involved in many cells (such as eosinophils, mast cells, T lymphocytes, neutrophils, airway epithelial cells, etc.) and cellular components. So far, it’s etiology and pathogenesis have not been fully elucidated. Compared with adolescent, the aged is another peak easy-to-onset phase of asthma. In recent years, the elderly population increasely grows, effective prevention and treatment of the elderly asthma has gradually become one of the focal issues. In terms of clinical manifestations and cellular immunity, there is a big difference between the aged and young people with asthma. Aging changes of asthma-related inflammatory cells may take part in the pathogenesis of asthma in the elderly. Here, the aging-related changes of these cells were reviewed. Authors hope to provide new ideas for the exploration of the pathogenesis of asthma in the elderly.