Peripheral arterial disease (PAD) is considered to be the main cause of limb disability and patient death, especially for the complex chronic total occlusion (CTO) in the occlusive lesions of the superficial femoral artery (SFA) of the lower limbs. Retrograde puncture technology for this type of disease application increases the cure rate. Vascular interventional cavity treatment has become the main way to solve this kind of disease, but many CTO lumen treatments will always encounter the failure of anterograde openness, or antegrade opened a longer under the intima so that you need to put a very long stent. Lower limb lesions are more complex. Stent restenosis is still a difficult problem when facing the cavity treatment, in particular, the rate of long-segment stent restenosis is particularly high. Using retrograde puncture technology can solve these clinical problems. The retrograde puncture technology existed long ago, but the reason for being less used in clinical practice is the limitation of the development of science and technology, complications of high, and the high clinical technical requirements. Recent years, with the development of science and technology, in the treatment of SFA occlusive lesions of lower limbs, especially involving long CTO, the use of retrograde puncture treatment has attracted more clinical attention.