Objective: The purpose of this study was to describe the use of a staged procedure that involved femoral artery catheterization, cesarean section delivery, uterine and placental embolization, and placenta removal as possible as we can for placenta previa accreta in order to prevent from hysterectomy. Methods: The current study includes 22 patients diagnosed as placenta previa accreta identified histologically after operation or confirmed by doctors through ultrasound results before operation and the findings during operation. Six patients underwent femoral artery catheterization before C-section. Artery embolization was conducted right away after the babies were delivered. Five patients had residual placenta tissues, receiving MTX therapy after operation. Other 16 patients underwent traditional methods, they failed and hysterectomy or cesarean-hysterectomy. Results: Twenty-two cases of placenta previa accreta were identified histologically or diagnosed by doctors who performed the surgery. Six cases successfully underwent prophylactic pelvic artery catheterization and embolization, the uteri were preserved. These cases had significant reductions in blood loss (2 300 vs. 5 375 mL; P=0.0004), units of MAP transfused (8 vs. 16.66; P=0.0108), the amount of plasma transfused (800 vs. 1 375 mL, P=0.0135). The total operation time was no different between the two groups. There were non-significant reductions in admission to the intensive care unit and length of hospital stay. Conclusion: We found that the successful use of prophylactic pelvic artery catheterization and embolization C-section procedure for placenta previa accreta is associated with decreased maternal morbidity and successfully preserved patient’s uteri.