文章摘要

老年恶性血液病患者的衰弱评估

作者: 1梁璐, 2薛华
1 河北大学附属医院急诊科，河北 保定 071000
2 河北大学附属医院血液科，河北 保定 071000
通讯: 薛华 Email: xh-xuehua@163.com
DOI: 10.3978/j.issn.2095-6959.2022.09.037
基金: 河北省财政厅卫生健康委老年病防治项目(2020)。

摘要

恶性血液病多发生于老年患者，衰老与恶性血液病的共同作用增加了衰弱的发生及治疗的复杂性。衰弱与较差的治疗反应、毒性增加和老年恶性血液病患者更差的生存率有关，这使得衰弱评估变得更加重要。通过适合的评估工具对老年患者进行衰弱评估有助于判断治疗的耐受性及预后，可为老年恶性血液病患者制定个体化治疗。恶性血液病为异质性疾病，需要根据疾病特点开发疾病特异性的衰弱评估工具。
关键词： 恶性血液病；衰老；衰弱评估；管理

Frailty assessment and management for elder adults with hematologic malignancies

Authors: 1LIANG Lu, 2XUE Hua
1 Department of Emergency, Affiliated Hospital of Hebei University, Baoding Hebei 071000, China
2 Department of Hematology, Affiliated Hospital of Hebei University, Baoding Hebei 071000, China

CorrespondingAuthor: XUE Hua Email: xh-xuehua@163.com

DOI: 10.3978/j.issn.2095-6959.2022.09.037

Foundation: This work was supported by the Senile Disease Prevention Project of Hebei Provincial Health Commission of Finance Department, China (2020).

Abstract

Hematological malignancies mostly occur in elderly patients, and the combined effects of aging and the mechanisms of hematological malignancies increase the complexity of frailty and treatment. Frailty is associated with poor therapeutic response, increased toxicity, and poor survival in elderly patients with hematological malignancies, making frailty assessment even more important. The frailty assessment of elderly patients with appropriate assessment tools can help determine the tolerance and prognosis of treatment, and can provide individualized treatment for elderly patients with hematological malignancies. Hematological malignancies are heterogeneous and require the development of disease-specific frailty assessment tools based on disease characteristics.

Keywords： hematologic malignancies; aging; frailty assessment; management

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